Effects of Stable Strontium in Treatment of Osteoporosis
During the 5-year period 1953 through 1957 a series of patients with osteoporosis seen at the Mayo Clinic were treated with strontium lactate (strontolac). The consideration that strontium lactate might be a useful adjunct in the treatment of this condition developed following a report by Shorr and Carter (1) that Sr2+ increases the retention of Ca2+ and that when the maximal normal Ca2+ absorption level is reached retention of Sr2+ increases in its turn, and further administration further heightens the retention of both elements. It has been our clinical impression that the few patients so treated have improved both subjectively and objectively during and following therapy. As clinical impressions are notoriously unreliable indexes of the adequacy of therapy, we have undertaken a study to compare the patient’s subjective complaints, the physical findings, and the roentgenograms of the spinal column from before a course of therapy with strontium lactate with those from after the treatment. The results of that study comprise this report.
KeywordsMayo Clinic Spinal Column Lumbar Vertebra Thoracic Vertebra Mayo Clinic Proceeding
Unable to display preview. Download preview PDF.
- 1.E. Shorr and A. C. Carter, The usefulness of strontium as an adjuvant to calcium in the remineralization of the skeleton in man. Bull. Hosp. Joint Dis. 13, 59–66 (1952).Google Scholar
- 2.D. A. Mackenzie and J. M. Janes, Postmenopausal osteoporosis. A programme of treatment in 42 cases. Can. M.A.J. 71, 339–340 (1954).Google Scholar