The Effects of Strontium and Calcium on Mammalian Collagenases

  • Jo Louise Seltzer
  • John J. Jeffrey
  • Arthur Z. Eisen


Collagen is the major structural protein of skin, bone, cartilage, tendon, and teeth. It is, in fact, the most abundant protein in the body. The collagen molecule consists of three polypeptide chains, molecular weight approximately 95,000 each, which are coiled together in a triple helix. Chemically, the collagen molecule is unique in that every third amino acid residue is glycine, and in that it contains relatively large amounts of hydroxyproline and hydroxylysine.


Organ Culture Human Skin Collagen Molecule Epidermolysis Bullosa Human Skin Fibroblast 
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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Jo Louise Seltzer
    • 1
  • John J. Jeffrey
    • 1
  • Arthur Z. Eisen
    • 1
  1. 1.Division of Dermatology, Department of MedicineWashington University School of MedicineSt. LouisUSA

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