Strontium and Histamine Secretion

  • J. C. Foreman


Histamine in mammalian tissues is largely stored within mast cells (1), which are connective tissue cells of unknown physiological function. Although mast cells essentially reside in connective tissue, in some species they float free in the fluid of the serous cavities such as the peritoneum. Peritoneal fluid from the rat, for example, is a source of free mast cells that can be separated from other cells and isolated for study. The basophil leukocytes of the blood also contain histamine and in some respects are similar to tissue mast cells. The question of whether the basophil leukocytes and mast cells are interchangeable and serve the same function remains unresolved and is beyond the scope of this discussion.


Mast Cell Phosphatidyl Serine Histamine Release Histamine Secretion Spontaneous Secretion 
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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • J. C. Foreman
    • 1
  1. 1.Department of PharmacologyUniversity College LondonLondonUK

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