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Strontium Ions and Membranes: Screening versus Binding at Charged Surfaces

  • Joseph S. D’Arrigo

Abstract

Sr2+ is one of several common alkaline earth cations that have been studied extensively over the the last decade in regard to their electrostatic effects on biological membranes. Much of this research work has centered on excitable membranes, where the presence of certain alkaline earths, particularly Ca2+, in the aqueous phase adjacent to the membrane is essential for its normal physiological behavior. However, the physicochemical mechanisms of alkaline earth action (i.e., screening and binding) that have been identified and elucidated for nerve and muscle membranes are known to also be applicable to certain artificial lipid bilayers (e.g., 1–3). Consequently, detailed consideration of the findings from past work exploring divalent cation action on excitable membranes offers appreciable insight into the types of electrostatic interaction commonly occurring between alkaline earth cations and charged membrane surfaces in general.

Keywords

Divalent Cation Surface Charge Density Giant Axon Threshold Potential Alkaline Earth Cation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Joseph S. D’Arrigo
    • 1
  1. 1.Department of PhysiologyUniversity of Hawaii School of MedicineHonoluluUSA

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