Relative Importance of Enteropathogens in Acute Endemic Diarrhea and Food-Borne Diarrheal Illness

  • Herbert L. DuPont
  • Larry K. Pickering
Part of the Current Topics in Infectious Disease book series (CTID)


Establishing the etiology of acute diarrhea is complex because of the many variables influencing its cause and/or detection, including age, geographic location, season, and availability of laboratory procedures necessary to fully identify the various agents. Regardless of the part of the world in which it occurs, acute infectious diarrhea cannot be attributed to any one enteropathogen. The presence of rotavirus (RV) in stool specimens of a substantial proportion of children with diarrhea is evidence of the importance of this agent in endemic illness. A correlation exists between identification of RV in stool specimens and serologic response to infection. Enterotoxigenic E. coli. (ETEC) is an important cause of diarrhea in persons from industrialized countries during travel to developing regions, but it does not account for a large number of endemic cases of diarrhea in children in the United States. Serotype-determined enteropathogenic E. coli (EPEC) is an important cause of infantile diarrhea, yet the relative frequency of occurrence and mechanisms of pathogenesis are unknown. Intestinal infections due to Shigella and Salmonella generally occur in the summer months in children over 3 months of age and in adults. G. lamblia is a cause of acute, chronic, and recurrent diarrhea in all age groups. Other agents which require specialized laboratory techniques for identification have been shown to cause diarrhea on occasion.


Diarrheal Disease Stool Specimen Halophilic Bacterium Yersinia Enterocolitica Acute Diarrhea 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Herbert L. DuPont
    • 1
  • Larry K. Pickering
    • 2
  1. 1.Program in Infectious Diseases and Clinical MicrobiologyThe University of Texas Health Science Center Medical SchoolHoustonUSA
  2. 2.Pediatric Infectious Diseases Program in Infectious Diseases and Clinical MicrobiologyThe University of Texas Health Science Center Medical SchoolHoustonUSA

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