• Herbert L. DuPont
  • Larry K. Pickering
Part of the Current Topics in Infectious Disease book series (CTID)


Giardia lamblia, a flagellated protozoan, was described in detail by Lambl in 1859.1 Although Lambl is credited with the discovery, Leeuwenhoek actually may have been the first to describe the agent in his own diarrheal stool in 1681.1 Initially, the agent was felt to be a normal inhabitant of the upper intestinal tract of humans,2 and it was considered to be nonpathogenic. Major support for its low-grade pathogenicity was offered by the finding of asymptomatic cyst excretion in nearly 10% of persons throughout the world. In the 1950s, a series of volunteer experiments3,4 established the infectivity of the protozoan. During the last two decades, G. lamblia has been shown to be an important cause of acute diarrhea in certain high-risk populations (particularly, American travelers to the Soviet Union, those traveling to developing parts of the world, and persons visiting ski resorts or camping areas of the Rocky Mountains) as well as the causative agent of recurrent and/or chronic diarrhea and malabsorption in all parts of the world.


Celiac Disease Stool Specimen Stool Examination Acute Diarrhea Duodenal Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Herbert L. DuPont
    • 1
  • Larry K. Pickering
    • 2
  1. 1.Program in Infectious Diseases and Clinical MicrobiologyThe University of Texas Health Science Center Medical SchoolHoustonUSA
  2. 2.Pediatric Infectious Diseases Program in Infectious Diseases and Clinical MicrobiologyThe University of Texas Health Science Center Medical SchoolHoustonUSA

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