Amebiasis

  • Herbert L. DuPont
  • Larry K. Pickering
Part of the Current Topics in Infectious Disease book series (CTID)

Abstract

Amebiasis is a ubiquitous disease which is a particularly important problem in developing tropical countries. The causative agent, Entamoeba histolytica, was first described in 1875 by Lösch, a Russian physician in St. Petersburg.1 He described the organisms in detail and called them Amebae coli. In a careful pathologic and clinical review in 1891, Councilman and Lefleur2 described amebic dysentery as a distinct entity characterized by ulceration of the colon wherein the ulcers were undermined without products of inflammation. They furthermore indicated that liver abscess often complicated intestinal disease with occasional extension of the abscess to the lung. The true pathogenic potential of E. histolytica for humans was established in 1911–1913 by a series of studies of experimental infection induced in volunteers.3,4 Filipino prison volunteers who ingested E. histolytica cysts developed dysentery, and stools were shown to contain the amebae. In 1919, the four species of commensal amebae were distinguished from E. histolytica.5

Keywords

Corticosteroid Iodine Radionuclide Diarrhea Sewage 

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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Herbert L. DuPont
    • 1
  • Larry K. Pickering
    • 2
  1. 1.Program in Infectious Diseases and Clinical MicrobiologyThe University of Texas Health Science Center Medical SchoolHoustonUSA
  2. 2.Pediatric Infectious Diseases Program in Infectious Diseases and Clinical MicrobiologyThe University of Texas Health Science Center Medical SchoolHoustonUSA

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