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Overview of Pituitary Tumor Treatment

  • Peter O. Kohler

Abstract

Major advances in the diagnostic and therapeutic approaches to pituitary tumors have occurred over the past two decades. As a result of the increased capacity to detect and treat pituitary microadenomas, the goals of treatment are now often different. Several years ago, the diagnosis of pituitary tumor was most often made in patients over 40 years of age.1 Frequently, the presenting complaints include visual defects, indicating relatively large tumors.2 In addition, most pituitary tumors were believed to be nonfunctional because (1) no hypersecretory syndrome was clearly identified in approximately 75% of patients and (2) on histological examination, the tumor cells showed no specific chromophilic hormone granules. The therapeutic goal in patients with these so-called “chromophobe adenomas” was often to prevent expansion or control tumor growth and avoid the visual and endocrine deficiencies caused by the mass effect of the tumor. Total resection of the tumor was not necessarily recommended because of the high incidence of complete pituitary dysfunction and fatality.3 Therapy for these tumors was usually either trans-frontal surgery,1 external irradiation,4 or a combination of both.5

Keywords

Pituitary Adenoma Pituitary Tumor Acromegalic Patient Transsphenoidal Surgery Sella Turcica 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Peter O. Kohler
    • 1
    • 2
  1. 1.University of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Little Rock Arkansas University HospitalLittle RockUSA

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