Endocrine Management after Pituitary Surgery

  • William E. Cobb


The detection and treatment of pituitary-hormone deficiencies constitutes a major part of patient management following surgery for pituitary and hypothalamic tumors. In the immediate postoperative period, the appearance of adrenocorticotropic hormone (ACTH) and/or thyroid-stimulating hormone (TSH) deficiency may be of little importance due to the routine use of corticosteroids and to the long plasma half-life of thyroxine, whereas acute deficiency of the posterior pituitary octapeptide, vasopressin, may result in a life-threatening disturbance of water balance. The management of ACTH, TSH, gonadotropin, and growth-hormone (GH) deficiencies assumes a greater significance in the long-term follow-up of patients beyond the immediate postoperative period. This chapter will review some basic concepts and recent developments in the perioperative use of corticosteroids and in the postoperative detection and treatment of pituitary-hormone deficiencies.


Diabetes Insipidus Human Growth Hormone Urine Osmolality Nephrogenic Diabetes Insipidus Pituitary Surgery 
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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • William E. Cobb
    • 1
    • 2
  1. 1.Department of Medicine, Division of EndocrinologyTufts-New England Medical Center HospitalBostonUSA
  2. 2.Quincy City HospitalQuincyUSA

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