Transsphenoidal Surgery for Pituitary Tumors

  • Kalmon D. Post


The transsphenoidal approach to the sella dates back to Schloffer,1 who in 1907 reported the decompression of a growth hormone (GH)-producing tumor via this route. He had modified the operation of Giordano2 by not resecting the frontal sinus or floor of the anterior fossa. Further modifications ensued, including a submucosal dissection,3 a sublabial incision,4 the use of a headlight,5 and image-intensified fluoroscopy.6 Hardy7–10 added the operating microscope and microsurgical techniques to the procedure, so that with minimal morbidity and mortality, both microadenomas and large tumors could be safely removed or decompressed while sparing the pituitary gland.


Pituitary Adenoma Pituitary Tumor Cavernous Sinus Transsphenoidal Surgery Normal Gland 


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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • Kalmon D. Post
    • 1
  1. 1.Department of Neurosurgery, Tufts-New England Medical Center HospitalTufts University School of MedicineBostonUSA

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