Abstract
Early in the 1960s Smith (1962) and Alexander and Moroson (1962) independently published experimental results indicating that absorption of ultraviolet light could induce cross-linking of protein to DNA in living cells. Since these initial observations there has been increasing experimental interest in photoinduced cross-linking of proteins to nucleic acids. Photobiologists are intrigued by the possibility that nucleic acid-protein cross-linking is an important mode of ultraviolet light induced damage in biological systems. Molecular biologists and biochemists interested in structural relations in nucleic-acid-protein systems (e.g., chromatin, ribosomes) are examining the feasibility of using UV-cross-linking as a means of determining contact points between nucleic acid and protein in these complexes. Photochemists are exploring the structures and mechanisms of formation of adducts of nucleic acid bases and related compounds with amino acids and amino acid analogs; these studies may have direct relevance to the goal of understanding the chemical basis of UV-induced cross-linking in nucleic acid-protein complexes.
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References
Abdurashidova, G. G., Turchinsky, M. F., Salikhov, T. A., Aslanov, K. A., and Budowsky, E. I., 1978, Identification of proteins which interact with tRNA at the A- and P-sites of the Escherichia coli ribosome, Bioorg. Khim. 4:982–983 (in Russian) [Chem. Abstr. 89:102393k (1978)].
Alberts, B., and Sternglanz, R., 1977, Recent excitement in the DNA replication problem, Nature 269:655–661.
Alcantara, R., and Wang, S. Y., 1965, Photochemistry of thymine in aqueous solution, Photochem. Photobiol. 4:473–476.
Alexander, P., and Moroson, H. L., 1962, Cross-linking of deoxyribonucleic acid to protein following ultra-violet irradiation of different cells, Nature 194:882–883.
Anderson, E., Nakashima, Y., and Konigsberg, W., 1975, Photo-induced cross-linkage of gene-5 protein and bacteriophage fd DNA, Nucleic Acids Res. 2:361–371.
Antonoff, R. S., and Ferguson, J. J., Jr., 1974, Photoaffinity labeling with cyclic nucleotides, J. Biol. Chem. 249:3319–3321.
Antonoff, R. S., Ferguson, J. J., Jr., and Idelkope, G., 1976, Direct photoaffinity labeling of cyclic nucleotide binding proteins with guanosine-3′,5′-monophosphate, Photochem. Photobiol. 23:327–329.
Antonoff, R. S., Obrig, T., and Ferguson, J. J., Jr., 1977, Direct photoaffinity labeling with cyclic nucleotides, in: Methods in Enzymology (W. B. Jakoby and M. Wilchek, eds.), Vol. 46, pp. 335–339, Academic Press, New York.
Azizova, O. A., Nikolaev, Y. V., Bakhmatova, V. I., Korol, B. A., Kayushin, L. P., and Kopylov, V. A., 1976, Free radicals in histones and nucleohistones under UV light, Stud. Biophys. 59:1–16 (in Russian) [Biol. Abstr. 63:35573 (1977); Chem. Abstr. 85:18799c (1976)].
Baca, O. G., and Bodley, J. W., 1976, U. V. induced cross-linking of E. coli ribosomal RNA to specific proteins, Biockem. Biophys. Res. Commun. 70:1091–1096.
Bartley, J. A., and Chalkley, R., 1972, The binding of deoxyribonucleic acid and histone in native nucleohistone, J. Biol. Chem. 247:3647–3655.
Ben-Ishai, R., Green, M., Graff, E., Elad, D., Steinmaus, H., and Salomon, J., 1973, Photoalkylation of purines in DNA, Photochem. Photobiol. 17:155–167.
Berman, H. M., Zacharias, D. E., Carrell, H. L., and Varghese, A. J., 1976, α-S-cysteinylthymine. A model for protein-nucleic acid cross-linking, Biochemistry 15:463–467.
Birnbaum, G. I., and Shugar, D., 1978, A purine nucleoside unequivocally constrained in the syn form: Crystal structure and conformation of 8-(α-hydroxyisopropyl)-adenosine, Biochim. Biophys. Acta 517:500–510.
Bradbury, E. M., 1977, Histone interactions and chromatin structure, in: The Organization and Expression of the Eucaryotic Genome (E. M. Bradbury and K. Javaherian, eds.), pp. 99–124, Academic Press, New York.
Braun, A., and Merrick, B., 1975, Properties of the ultraviolet light mediated binding reaction of bovine serum albumin with DNA, Photochem. Photobiol. 21:243–248.
Brimacombe, R., Stöffler, G., and Wittmann, H. G., Ribosome structure, Ann. Rev. Biochem. 47:217–250.
Budowsky, E. I., Simukova, N. A., Turchinsky, M. F., Boni, I. V., and Skoblov, Y. M., 1976, Induced formation of covalent bonds between nucleoprotein components. 5. UV or bisulfite induced polynucleotide-protein crosslinkage in bacteriophage MS-2, Nucleic Acids Res. 3:261–276.
Budzik, G. P., Lam, S. M., Schoemaker, H. J. P., and Schimmel, P. R., 1975, Two photo-crosslinked complexes of isoleucine specific transfer RNA with amino-acyl transfer RNA synthetase, J. Biol. Chem. 250:4433–4439.
Campbell, J. M., Schulte-Frohlinde, D., and Von Sonntag, C., 1974, Radiation chemistry of DNA model compounds. VI. Quantum yields in the UV photolysis of 5-bromouracil in the presence of hydrogen donors,. Photochem. Photobiol. 20:465–467.
Celis, J. E., Fink, M., and Kaltoft, K., 1976, On the use of ultraviolet light to study protein-DNA cross-linking. Nucleic Acids Res. 3:1065–1071.
Champoux, J. J., 1978, Proteins that affect DNA conformation, Ann. Rev. Biochem. 47:449–479.
Coleman, J. E., and Armitage, I. A., 1978, Tyrosyl-base-phenylalanyl intercalation in gene 5 protein-DNA complexes: Proton nuclear magnetic resonance of selectively deuterated gene 5 protein, Biochemistry 17:5038–5045.
Cooperman, B. S., 1975, Photoaffinity labeling of proteins and more complex receptors, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 315–340, Plenum Press, New York.
Cooperman, B. S., 1977, Identification of binding sites on the E. coli ribosome by affinity labeling, in: Protein Crosslinking (M. Friedman, ed.), pp. 595–609, Plenum Press, New York.
Cutler, R. G., 1976, Crosslinkage hypothesis of aging: DNA adducts in chromatin as a primary aging process, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 443–492, Plenum Press, New York.
DeLange, R. J., Williams, L. C., and Martinson, H. G., 1979, Identification of interacting amino acids at the histone 2A–2B binding site, Biochemistry, 18:1942–1946.
Dixon, C. J., and Grant, D. W., 1973, The photolysis of cystine in acidic aqueous solution, Photochem. Photobiol. 18:387–391.
Ehresmann, B., Reinbolt, J., and Ebel, J. P., 1975, Studies of the binding of E. coli ribosomal protein S4 to 16S rRNA after UV irradiation of the S4–16S rRNA complex, FEBS Lett. 58:106–111.
Ehresmann, B., Reinbolt, J., Backendorf, C., Tritsch, D., and Ebel, J. P., 1976, Studies of the binding sites of Escherichia coli ri bosom al protein S7 sites with 16S RNA by ultraviolet irradiation, FEBS Lett. 67:316–319.
Ehresmann, B., Backendorf, C., Ehresmann, E., and Ebel, J. P., 1977, Characterization of the regions from E. coli 16S RNA covalently linked to ribosomal proteins S4 and S20 after ultraviolet irradiation, FEBS Lett. 78:261–266.
Ekert, B., and Giocanti, N., 1977, Formation of covalent bonds between nucleic acid and protein ribosome components ofEscherichia coli MRE-600 following gamma-irradiation, Int. J. Radiat. Biol. 31:303–319.
Ekpenyong, K. I., and Shetlar, M. D., 1979, Photochemical reactions of cytosine N-methyl analogs in alcoholic solution, Photochem. Photobiol., in press.
Ekpenyong, K. I., Meyer, R. B. Jr., and Shetlar, M. D., 1978, Photochemically induced reaction of l, N 4-dimethylcytosine with isopropanol, Tetrahedron Lett., 1619–1622.
Elad, D., 1972, Photochemical substitutions in purine and purine nucleosides, in: Jerusalem Symposium on Quantum Chemistry and Biochemistry (E. Bergmann and B. Pullman, eds.), Vol. 4, pp. 412–417, Academic Press, New York.
Elad, D., 1976, Photochemically induced adducts of DNA, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 243–266, Plenum Press, New York.
Elad, D., 1977, Reaction selectivity and molecular association in photochemical reactions of nucleic acids and their constituents, Pure App. Chem. 49:503–509.
Elad, D., and Rosenthal, I., 1968, Photochemical hydrogenation of uracil and 1,3-dimethyluracil, Chem. Commun., 879.
Elad, D., and Rosenthal, I., 1969, Photochemical alkylation of caffeine with amino acids, J. Chem. Soc. D. Chem. Commun., 905–906.
Elad, D., and Salomon, J., 1971, Ultraviolet- and radiation-induced reactions of caffeine with amines, Tetrahedron Lett., 4783–4784.
Ewig, R. A. G., and Kohn, K. W., 1978, DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells, Cancer Res. 38:3197–3203.
Felsenfeld, G., 1978, Chromatin, Nature 271:115–122.
Fiser, I., Scheit, K. H., Stöffler, G., and Kuechler, E., 1974, Identification of protein S1 at the messenger RNA binding site of the E. coli ribosome, Biochem. Biophys. Res. Commun. 60:1112–1118.
Fiser, I., Margaritella, P., and Kuechler, E., 1975a, Photoaffinity reaction between polyuridylic acid and protein S1 on the Escherichia coli ribosome, FEBS Lett. 52:281–283.
Fiser, I., Scheit, K. H., Stöffler, G., and Kuechler, E., 1975b, Proteins at the RNA binding site of the E. coli ribosome, FEBS Lett. 56:226–229.
Fiser, I., Scheit, K. H., and Kuechler, E., 1977, Poly(4-thiouridylic acid) as messenger RNA and its application for photoaffinity labeling of the ribosomal mRNA binding site, Eur. J. Biochem. 74:447–456.
Fisher, G. J., and Johns, H. E., 1976. Pyrimidine photohydrates, in: Photochemistry and Photobiology of Nucleic Acids (S. Y. Wang, ed.), Vol. 1, pp. 169–224, Academic Press, New York.
Fisher, G. J., Varghese, A. J., and Johns, H. E., 1974, Ultraviolet-induced reactions of thymine and uracil in the presence of cysteine, Photochem. Photobiol. 20:109–20.
Fletchner, T. W., 1977, Photochemical solvent addition to 2(5H)-furanone: Hydrocarbon solvents, J. Org. Chem. 42:901–903.
Forbes, W. F., and Savige, W. E., 1962, Photolysis and photo-oxidation of amino acids and peptides. I. Irradiation of aqueous solutions of cystine with sunlight and other ultraviolet light sources, Photochem. Photobiol. 1:1–13.
Fornace, A. J., Jr., and Kohn, K. W., 1976, DNA-protein cross-linking by ultraviolet radiation in normal human and xeroderma pigmentosum fibroblasts, Biochim. Biophys. Acta 435:95–103.
Fourrey, J. L., 1976, Thiocarbonyl photochemistry. VI. Light induced addition of a primary amine to 4-thiouracil derivatives, Tetrahedron Lett., 297–300.
Fourrey, J. L., and Jouin, P., 1973, Thiocarbonyl photochemistry. I. Hydroxyalkylation of 1,3-dimethyl-4-thiouracil, Tetrahedron Lett., 3225–3227.
Fourrey, J. L., and Jouin, P., 1977, Photochemistry of uridine in methanol. Substituent and concentration effects, Tetrahedron Lett., 3397–3400.
Freifelder, D., 1976, Physical Biochemistry: Applications to Biochemistry and Molecular Biology, W. H. Freeman, San Francisco.
Friedman, M., 1977, Cross-linking amino acids-stereochemistry and nonmenclature, in: Protein Cross-Linking (M. Friedman, ed.), Part A, pp. 1–27, Plenum Press, New York.
Frimer, A. A., Havron, A., Leonov, D., Sperling, J., and Elad, D., 1976, Ultraviolet and 7-ray induced free radical reactions of nucleic acid constituents. Selectivity of some reactions for purines. Suppression of the reactivity of pyrimidines, J. Amer. Chem. Soc. 98:6026–33.
Frischauf, A. M., and Scheit, K. H., 1973, Affinity labeling of E. coli RNA polymerase with substrate and template analogs, Biochem. Biophys. Res. Commun. 53:1227–1233.
Glatzer, L., Rincon, D. A., and Eisenstark, A., 1976, The binding of near-ultraviolet light-induced tryptophan photo-products to DNA, Biochim. Biophys. Acta 418:137–145.
Goeddel, D. V., Yansura, D. G., and Caruthers, M. H., 1978, How lac repressor recognizes DNA, Proc Nat. Acad. Sci. USA 75:3578–3582.
Gordon, J. S., Bell, G. I., Martinson, H. G., and Rutter, W. J., 1976, Selective interaction of 5’-bromodeoxyuridine-substituted DNA with different chromosomal proteins, Biochemistry 15:4778–4786.
Gordon, M. P., 1976, Role of protein in the inactivation of viruses by ultraviolet radiation, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 105–122, Plenum Press, New York.
Gorelic, L., 1975a, Photoinduced covalent crosslinkage, in situ, of Escherichia coli 50S ribosomal proteins to RNA, Biochim. Biophys. Acta 390:209–225.
Gorelic, L., 1975b Evidence for photoinduced cross-linkage, in situ, of 30S ribosomal proteins to 16S rRNA, Biochemistry 14:4627–4633.
Gorelic, L., 1976a, Photoinduced cross-linkage, in situ, of E. coli 30S ribosomal proteins to 16S RNA: Identification of cross-linked proteins and relationships between reactivity and ribosome structure, Biochemistry 15:3579–3590.
Gorelic, L., 1976b, Analysis of the kinetics of photoinduced crosslinkage of the protein and RNA components of the Escherichia coli 50S ribosomal subunit, Biochim. Biophys. Acta 454:185–192.
Gorelic, L., 1976c, Demonstration of ribosome-dependent photoinduced chain breakage of the 16S ribosomal ribonucleic acid component of the Escherichia coli 30S ribosomal subunit, Biochemistry 15:5474–5480.
Gorelic, L., 1977, Photoinduced nucleic acid-protein crosslinkage in ribosomes and ribosome complexes, in: Protein Crosslinking (M. Friedman, ed.). Part A, pp. 611–631, Plenum Press, New York.
Gorelic, L., and Parker, D., 1978, Studies of the effects of ultraviolet radiation on the structural integrities of ribosomal RNA components of the Escherichia coli 50S ribosomal subunit, Biochemistry 17:3152–3162.
Gorelic, L. S., Lisagor, P., and Yang, N. C., 1972, The photochemical reactions of 1,3,-dimethyluracil with 1-aminopropane and poly-L-lysine, Photochem. Photobiol. 16:465–480.
Green, M., and Cohen, S. S., 1957, Studies on the biosynthesis of bacterial and viral pyrimidines. III. Derivatives of dihydrocytosine, J. Biol. Chem. 228:601–609.
Grossweiner, L. I., 1976, Photochemical inactivation of enzymes, in: Current Topics in Radiation Research (M. Ebert and A. Howard, eds.), Vol. 11, pp. 141–199, North-Holland Publishing, Amsterdam.
Habazin, V., and Han, A., 1970, Ultraviolet light-induced DNA-to-protein cross-linking in HeLa cells, Int. J. Radiat. Biol. 17:569–575.
Hamelin, C., Sarhan, F., and Chung, Y. S., 1977, Ozone-induced DNA degradation in different DNA polymerase I mutants of Escherichia coli K12, Biochem. Biophys. Res. Commun. 77:220–224.
Han, A., 1973, Cell cycle dependent effects of ultraviolet light. I. Mammalian cells, Stud. Biophys. 36/37:127–137.
Han, A., Korbelik, M., and Ban, J., 1975, DNA-to-protein cross-linking in synchronized HeLa cells exposed to ultraviolet light, Int. J. Radiat. Biol. 27:63–74.
Havron, A., and Sperling, J., 1977, Specificity of photochemical cross-linking in protein-nucleic acid complexes: Identification of the interacting residues in RNase-pyrimidine nucleotide complex, Biochemistry 16:5631–5635.
Havron, A., Sperling, J., and Elad, D., 1976, Reactivity and selectivity in light-induced free radical reactions of 2-propanol with purine and pyrimidine mononucleotides and dinu-cleoside phosphates, Nucleic Acids Res. 3:1715–1725.
Hawkins, R. B., 1976, The measurement of ionizing radiation-induced cross-linkage of DNA and protein in bacteriophage, Radiat. Res. 68:300–307.
Hélène, C., 1975, Metal ion-mediated specific interactions between nucleic acid bases of polynucleotides and amino acid side chains of polypeptides, Nucleic Acid Res. 2:961–969.
Hélène, C., 1976, Photosensitized cross-linking of proteins to nucleic acids, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 149–163, Plenum Press, New York.
Hélène, C., 1977a, Excited state interactions and photochemical reactions in protein-nucleic acid complexes, in: Research in Photobiology (A. Castellani, ed.), pp. 31–39, Plenum Press, New York.
Hélène, C., 1977b, Specific recognition of guanine bases in protein-nucleic acid complexes, FEBS Lett. 74:10–13.
Hélène, C., 1977c, Mechanisms of quenching of aromatic amino acid fluorescence in protein-nucleic acid complexes, in: Excited States in Organic Chemistry and Biochemistry (B. Pullman and N. Goldblum, eds.), pp. 65–78, D. Reidel, Boston.
Hélène, C., and Douzou, P., 1964, Reversible photochemical reactions of cytosine in alcoholic solution, C. R. Acad. Sci. (Paris) 258:196–198.
Hélène, C., Haug, A., Delbruck, M., and Douzou, P., 1964, Summary of evidence on the tautomeric forms of cytosine, C. R. Acad. Sci. (Paris) 259:3385–3388.
Hélène, C., Toulme, F., Charlier, M., and Yaniv, M., 1976, Photosensitized splitting of thymine dimers in DNA by gene 32 protein from phage T4, Biochem. Biophys. Res. Commun. 71:91–98.
Hillel, Z., and Wu, G.-W., 1978, Photochemical cross-linking studies on the interaction of Escherichia coli RNA polymerase with T7 DNA, Biochemistry 17:2954–2961.
Holmes, R. E., and Robins, R. K., 1964, Purine nucleosides. VII. Direct bromination of adenosine, deoxyadenosine, guanosine, and related purine nucleosides, J. Amer. Chem. Soc. 86:1242–1245.
Hutchinson, F., 1973, The lesions produced by ultraviolet light in DNA containing 5-bromouracil, Quart. Rev. Biophys. 6:201–246.
Huyser, E. S., 1970, Free-Radical Chain Reactions, Wiley-Interscience, New York.
Jackson, D. S., 1978, Biosynthesis of collagen, International Rev. Biochem. 18:233–259.
Jakoby, W. B., and Wilchek, M., eds., 1977, Affinity Labeling, Methods in Enzymology, Vol. 46, Academic Press, New York.
Jellinek, T., and Johns, R. B., 1970, The mechanism of photochemical addition of cysteine to uracil and formation of dihydrouracil, Photochem. Photobiol. 11:349–359.
Jocelyn, P. C., 1971, Biochemistry of the SH Group, Academic Press, New York.
Jori, G., and Spikes, J. D., 1978, Mapping the three-dimensional structure of proteins by photochemical techniques, Photochem. Photobiol. Rev. 3:193–275.
Jovin, T. M., 1976, Recognition mechanisms of DNA-specific enzymes, Ann. Rev. Biochem. 45:889–920.
Kaneko, M., Matsuyama, A., and Nagata, C., 1978, Tyrosine-sensitized photodimerization of thymine in aqueous solution, Photochem. Photobiol. 27:359–361.
Kohn, K. W., 1979, DNA as a target in cancer chemotherapy: measurement of macromolecular DNA damage produced in mammalian cells by anticancer agents and carcinogens, in: Methods in Cancer Research (V. T. DeVita, Jr., and H. Busch, eds.), Vol. 16, Part A, pp. 291–345, Academic Press, New York.
Romberg, R. D., 1977, Structure of chromatin, Ann. Rev. Biochem. 46:931–954.
Kornhauser, A., 1975, UV-induced DNA-protein cross-links in vitro and in vivo, Photochem. Photobiol. 23:457–460.
Kornhauser, A., Pathak, M. A., Zimmermann, E., and Szabo, G., 1976, The in vivo effect of ultraviolet irradiation (290–350 nm) on epidermal chromatin, Croat. Chem. Acta 48:385–390.
Kunkel, G. R., and Martinson, H. G., 1978, Histone-DNA interactions within chromatin: Isolation of histone from DNA-histone adducts induced in nuclei by UV light, Nucleic Acids Res. 5:4263–4272.
Lapeyre, J.-N., and Bekhor, I., 1974, Effects of 5-bromo-2’-deoxyuridine and dimethyl sulfoxide on properties and structure of chromatin, J. Mol. Biol. 89:137–162.
Lapeyre, J.-N., and Bekhor, I., 1976, Chromosomal protein interactions in chromatin and with DNA, J. Mol. Biol. 104:25–58.
Leonov, D., and Elad, D., 1974a, Ultraviolet and 7-ray-induced reactions of nucleic acid constituents: Reactions of purines with ethers and dioxalane, J. Org. Chem. 39:1470–1473.
Leonov, D., and Elad, D., 1974b, Photochemical and 7-ray-induced reactions of nucleic acid constituents: Suppression of the reactivity of pyrimidine in the presence of purines, J. Amer. Chem. Soc. 96:5635–5637.
Leonov, D., and Elad, D., 1977, Light-induced free radical alkylation of polynucleotides and their enzymatic digestion, Nucleic Acids Res. 4:319–326.
Leonov, D., Salomon, J., Sasson, D., and Elad, D., 1973, Ultraviolet- and 7-ray-induced reactions of nucleic acid with alcohols: On the selectivity of these reactions for purines, Photochem. Photobiol. 17:465–468.
Lica, L., and Ray, D. S., 1977, Replication of bacteriophage M13. XII. In vivo cross-linking of a phage-specific DNA binding protein to the single stranded DNA of bacteriophage M13 by ultraviolet irradiation, J. Mol. Biol. 115:45–59.
Lin, S.-Y., and Riggs, A. D., 1974, Photochemical attachment of lac repressor to bromodeoxyuridine-substituted lac operator by ultraviolet radiation, Proc. Nat. Acad. Sci. USA 71:947–951.
Lin, S.-Y., Lin, D., and Riggs, A. D., 1976, Histones bind more tightly to bromodeoxyuridine-substituted DNA than to normal DNA, Nucleic Acids Res. 3:2183–2191.
Lindsay, R. H., Paik, W. K., and Cohen, P. P., 1962, Hydrolytic degradation of purine derivatives to glycine, Biochim Biophys. Acta 58:585–587.
Livneh (Noy), E., Elad, D., and Sperling, J., 1978, Light-induced free-radical reactions of nucleic acid constituents: Effect of sequence and base-base interactions on the reactivity of purines and pyrimidines in ribonucleotides, Biochemistry 17:2138–3133.
Long, L. M., 1947, 8-R-thio- and 8-R-sulfonyl caffeine derivatives, J. Amer. Chem. Soc. 69:2939–2941.
Lorberbaum, Z., Sperling, J., and Elad, D., 1976, The selective photoinitiated alkylation of purines in DNA with 2-propylamine, Photochem. Photobiol. 24:389–391.
Margaritella, P., and Kuechler, E., 1978, Specificity of photo-cross-linking reaction between poly-U and protein S1 on Escherichia coli ribosome. FEBS Lett. 88:131–134.
Markovitz, A., 1972, Ultraviolet light-induced stable complexes of DNA and DNA polymerase, Biochem. Biophys. Acta 281:522–534.
Martinson, H. G., Shetlar, M. D., and McCarthy, B. J., 1976, Histone-histone interactions within chromatin: Cross-linking studies using ultraviolet light, Biochemistry 15:2002–2007.
Matsuyama, A., and Nagata, C., 1970, Triplet-triplet energy transfer from histone to DNA in deoxyribonucleohistone, Biochim. Biophys. Acta 224:588–596.
Maurizot, J. C., Boubault, G., and Hélène, C., 1978a, Interaction between the peptide lysyltryptophanyl-lysine and copolynucleotides of adenine and uracil: Selectivity of interaction, FEBS. Lett. 88:33–36.
Maurizot, J. C., Boubault, G., and Hélène, C., 1978b, Interaction of aromatic residues of proteins with nucleic acids: Binding of oligopeptides to copolynucleotides of adenine and cytosine, Biochemistry 17:2096–2101.
Minsky, B. D., and A. Braun, 1977, X-ray-mediated cross-linking of protein and DNA, Radiat. Res. 71:505–515.
Möller, K., and Brimacombe, R., 1975, Specific cross-linking of proteins S7 and L14 to ribosomal RNA by UV irradiation of E. coli ribosomal subunits, Mol. Gen. Genet. 141:343–355.
Montenay-Garestier, T., Brun, F., and Hélène, C., 1976, Interaction of disulfide groups with nucleic acid bases, Photochem. Photobiol. 23:87–91.
Moore, A. M., and Thomson, C. H., 1956, Photodecomposition of pyrimidine compounds, in: Progress in Radiobiology (J. S. Mitchell, B. E. Holmes, and C. L. Smith, eds.), pp. 75–81, Oliver and Boyd, London.
Morin, N. R., Zeldin, P. E., Kubinski, Z. O., Bhattacharya, P. K., and Kubinski, H., 1977, Macromolecular complexes produced by chemical carcinogens and ultraviolet radiation, Cancer Res. 37:3802–3814.
Muel, B., and Langlois, E., 1975, Photochemical copolymerization of tyrosine and uracil, in: Abstracts of the International Symposium on “Protein and Other Adducts to DNA,” Williamsburg, Virginia, May 2–6, 1975.
Myers, L. S., Jr., 1976, Ionizing radiation induced attachment reactions of nucleic acids and their components, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 261–286, Plenum Press, New York.
Nakashima, Y., and Konigsberg, W., 1975, Photoinduced cross-linkage of gene-5 protein and fd DNA, in: Abstracts of the International Symposium on “Protein and Other Adducts to DNA,” Williamsburg, Virginia, May 2–6, 1975.
Novak, R. L., and Dohnal, J., 1974, Interaction of tyrosyl, histidyl, and tryptophanyl peptides with DNA: Specificity and mechanism of the interaction, Nucleic Acid Res. 1:761–766.
Obrig, T., Antonoff, R. S., Kirwin, K. S., and Ferguson, J. J., 1975, The binding of adenosine-3’-5’-monophosphate by messenger ribonucleoprotein-like particles, Biochem. Biophys. Res. Commun. 66:437–443.
Ogata, R., and Gilbert, W., 1977, Contacts between the lac repressor and thymine in the lac operator, Proc. Nat. Acad. Sci. USA 74:4973–4976.
Ogilvie, K. K., and Thompson, E. A., 1976. Photoreaction of O 2, 2′-anhydro-uridine with ethanol, Photochem. Photobiol. 24:81–82.
Owada, M., Ihara, S., Toyoshima, K., Kozai, Y., and Sugino, Y., 1976, Ultraviolet inactivation of avian sarcoma viruses: Biological and biochemical analysis, Virology 69:710–718.
Paradiso, P., Nakashima, Y., and Königsberg, W., 1978, Photo-induced crosslinking of gene-5 protein to DNA, in: Biomolecular Structure and Function (P. F. Agris, ed.), pp. 581–587, Academic Press, New York.
Pogany, G. C., 1976, Analysis of a Hertwig effect induced by the irradiation of Rana pipeins sperm with ultraviolet, Dev. Growth Differ. 18:339–348.
Pon, C. L., Brimacombe, R., and Gualerzi, C., 1977, Cross-linking of Escherichia coli initiation factor IF-3 to the RNA moiety of the 30S ribosomal subunit, Biochemistry 16:5681–5686.
Portalier, R., and Worcel, A., 1976, Association of the folded chromosome with the cell envelope of E. coli: Characterization of the proteins at the DNA-membrane attachment site, Cell 8:245–255.
Rahn, R. O., and Patrick, M. H., 1976, Photochemistry of DNA; Secondary structure, photosensitization, base substitution, and exogeneous molecules, in: Photochemistry and Photobiology of Nucleic Acids (S. Y. Wang, ed.), Vol. 2, pp. 97–145, Academic Press, New York.
Reboud, A.-M., Buisson, M., Marion, M.-J., and Reboud, J. P., 1978, Photo-induced protein-RNA cross-linking in mammalian 40S ribosomal subunits, Eur. J. Biochem. 90:421–426.
Reeve, A. E., and Hopkins, T. R., 1975, Photochemical reactions of nucleic acid bases sensitized by tryptophan, in: Abstracts of the International Symposium on “Proteins and Other Adducts to DNA,” Williamsburg, Virginia, May 2–6, 1975.
Rich, A., 1977, An overview of protein-nucleic acid interaction, in: Nucleic Acid-Protein Recognition (H.J. Vogel, ed.), pp. 3–11, Academic Press, New York.
Rinke, J., Yuki, A., and Brimacombe, R., 1976, Studies on the environment of protein S7 within the 30S subunit of Escherichia coli ribosomes, Eur. J. Biochem. 64:77–89.
Rohrback, M. S., and Bodley, J. W., 1977, Photo-cross-linking of guanine nucleotides to the nucleotide binding site of elongation factor G, Arch. Biochem. Biophys. 183:340–46.
Rosenthal, I., Poupko, R., Muszkat, K. A., and Sharafi-Ozeri, S., 1976, Adenosine-sensitized photolysis of carboxylic acids in frozen aqueous solution, J. Phys. Chem. 80:454–456.
Rupp, W. D., and Prusoff, W. H., 1965, Photochemistry of iodouracil. Effects of sulfur compounds, ethanol and oxygen, Biochem. Biophys. Res. Commun. 18:158–164.
Ryang, H.-S., and Wang, S. Y., 1978, α-Diketone sensitized photooxidation of pyrimidines, J. Amer. Chem. Soc. 100:1302–1303.
Saito, I., Ito, S., and Matsuura, T., 1978a, Photo-induced coupling reactions of 5-bromo-uridine to tryptophan derivatives, J. Amer. Chem. Soc. 100:2901–2902.
Saito, I., Ito, S., and Matsuura, T., 1978b, A new direct method for introduction of indolyl groups at the 5-position of uridine. Photochemical synthesis of model compounds for nucleic acid-protein adducts, Tetrahedron Lett. 1978:2585–2588.
Salomon, J., and Elad, D., 1973, Photochemical reactions of nucleic acid components. Peroxide-initiated reactions of purines with alcohols, J. Org. Chem. 38:3420–3421.
Salomon, J., and Elad, D., 1974a, Selective photochemical alkylation of purines in DNA, Biochem. Biophys. Res. Commun. 58:890–894.
Salomon, J., and Elad, D., 1974b, Ultraviolet and 7-ray-induced reactions of nucleic acid constituents. Reactions of purines with amines, Photochem. Photobiol. 19:21–27.
Sato, E., Koyama, K., and Kanaoka, Y., 1971, Photoinduced reactions IV. Photoreduction of uracil derivatives in formic acid, Chem. Pharm. Bull. (Tokyo) 19:837–839.
Sawada, F., 1975, Covalent attachment of 4-thiouridylic acid to ribonuclease A by near-ultraviolet radiation, Biochem. Biophys. Res. Commun. 64:311–316.
Schenkman, M. I., Ward, D. C., and Moore, P. B., 1974, Covalent attachment of a messenger RNA to the Escherichia coli ribosome, Biochim. Biophys. Acta 353:503–508.
Schiaffonati, L., Tsutsui, Y., Chang, S. D., and R. Baserga, 1978, Effect of 5-bromodeoxyuridine on deoxyribonucleic acid-protein adducts induced by ultraviolet light in chromatin and cells, Lab. Invest. 38:58–67.
Schimmel, P. R., and Budzik, G. P., 1977, Photocross-linking of protein-nucleic acid complexes, in: Methods in Enzymology (W. B. Jakoby and M. Wilchek, eds.), Vol. 46, pp. 168–180, Academic Press, New York.
Schimmel, P. R., Budzik, G. P., Lam, S. M., and Schoemaker, H. J. P., 1976, In vitro studies of photochemically linked protein-nucleic acid complexes. Determination of cross-linked regions and structural relationships in specific complexes, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 123–148, Plenum Pres, New York.
Schoemaker, H. J. P., and Schimmel, P. R., 1974, Photoinduced joining of a transfer RNA with its conjugate aminoacyl-transfer RNA synthetase, J.Mol. Biol. 84:503–513.
Schoemaker, H. J. P., Budzik, G. I., Giege, R. C., and Schimmel, P. R., 1975, Three photocross-linked complexes of yeast phenylalanine specific transfer RNA with aminoacyl-transfer RNA synthetases, J. Biol. Chem. 250:4440–4444.
Schott, H. N. and Shetlar, M. D., 1974, Photochemical addition of amino acids to thymine, Biochem. Biophys. Res. Commun. 59:1112–1116.
Shafferman, A., and Stein, G. 1974, The effect of aromatic amino acids on the photochemistry of a disulfide: Energy transfer and reactions with hydrated electrons, Photochem. Photobiol. 20:399–406.
Shapiro, R., 1976, Addition of amino acids and related substances to nucleic acids by nucleophilic catalysis, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 225–242, Plenum Press, New York.
Shapiro, R., and Gazit, A., 1977, Cross-linking of nucleic acids and proteins by bisulfite, in: Protein Cross-Linking (M. Friedman, ed.), Part A, pp. 633–640; Plenum Press, New York.
Shetlar, M. D., 1975a, The photoreaction of N, N-1,3-dimethyluracil with ethanol, Tetrahedron Lett., 477–480.
Shetlar, M. D., 1975b, Photoaddition of tetrahydrofuran to 1,3-dimethyluracil, Chem. Commun., 653–654.
Shetlar, M. D., 1975c, Photoinduced reactions of 1,3-dimethylthymine and 1,3-dimethyluracil with various small molecules, in: Abstracts of the International Symposium on “Proteins and Other Adducts to DNA,” Williamsburg, Virginia, May 2–6, 1975.
Shetlar, M. D., 1976, The photoreactions and free radical induced reactions of 1,3-dimethyluracil in methanol and other alcohols, Photochem. Photobiol. 24:315–319.
Shetlar, M. D., 1979, Photochemical and free radical initiated reactions of 1,3-dimethylthymine with isopropanol, Photochem. Photobiol. 29:253–260.
Shetlar, M. D., Schott, H. N., Martinson, H. G., and Lin, E. T., 1975, Formation of thymine-lysine adducts in irradiated DNA-lysine systems, Biochem. Biophys. Res. Commun. 66:88–93.
Shima, A., and Sugahara, T., 1976, Age-dependent ploidy class changes in mouse hepatocyte nuclei as revealed by Feulgen-DNA cytofluorometry, Exp. Geront. 11:193–203.
Shugar, D., and Wierzchowski, K. L., 1958, Photochemistry of nucleic acids, nucleic acid derivatives, and related compounds, Postepy. Biochem. 4(Suppl.):243–296.
Simukova, N. A., and Budowsky, E. I., 1974, Conversion of non-covalent interactions in nucleoproteins into covalent bonds: UV-induced formation of polynucleotide-protein cross-links in bacteriophage Sd virions, FEBS Lett. 38:299–303.
Sklobovskaya, M. V., and Ryabchenko, N. I., 1970a, Reduction of the yield of DNA in the deproteinization of UV or gamma-irradiated solutions of deoxyribonucleoproteins. I. Dependence of the magnitude of the effect on the complexation of DNA with protein, Radiobiologiya 10:14–18.
Sklobovskaya, M. V., and Ryabchenko, N. I., 1970b, Reduction of the yield of DNA in the deproteinization of UV or gamma-irradiated solutions of deoxyribonucleoprotein. II. Some problems of the formation of damage, Radiobiologiya 10:332–337.
Smets, L. A. and Cornelis, J. J., 1971, Repairable and irrepairable damage in 5-bromouracil-substituted DNA exposed to ultraviolet radiation, Int. J. Radiat. Biol. 19:445–457.
Smith, K. C., 1962, Dose-dependent decrease in extractability of DNA from bacteria following irradiation with ultraviolet light or visible light plus dye, Biochem. Biophys. Res. Commun. 8:157–163.
Smith, K. C., 1964a, The photochemical interaction of deoxyribonucleic acid and protein in vivo and its biological importance, Photochem. Photobiol. 3:415–427.
Smith, K. C., 1964b, Photochemistry of the nucleic acids, Photophysiology 3:329–388.
Smith, K. C., 1967, Biologically important damage to DNA by photoproducts other than cyclobutane-type thymine dimers, in: Radiation Research (G. Silini, ed.), pp. 756–770, North-Holland Publishing Co., Amsterdam.
Smith, K. C., 1968, The biological importance of UV-induced DNA-protein cross-linking in vivo and its probable chemical mechanisms, Photochem. Photobiol. 7:651–60.
Smith, K. C., 1969, Photochemical addition of amino acids to 14C-uracil, Biochem. Biophys. Res. Commun. 34:354–357.
Smith, K. C., 1970, A mixed photoproduct of thymine and cysteine: 5-S-cysteine, 6-hydrothymine, Biochem. Biophys. Res. Commun. 39:1011–1016.
Smith, K. C., 1976a, Radiation-induced addition of proteins and other molecules to nucleic acids, in: Photochemistry and Photobiology of Nucleic Acids (S. Y. Wang, ed.), pp. 187–218, Academic Press, New York.
Smith, K. C., 1976b, Chemical adducts to deoxyribonucleic acid. Their importance to the genetic alteration theory of aging, Interdiscipl. Topics Geront. 9:16–24.
Smith, K. C., 1976c, Radiation-induced cross-linking of DNA and protein in bacteria, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 67–81, Plenum Press, New York.
Smith, K. C., and Aplin, R. T., 1966, A mixed photoproduct of uracil and cysteine (5-S-cysteine-6-hydrouracil). A possible model for the in vivo cross-linking of DNA and protein by UV light, Biochemistry 5:2125–2130.
Smith, K. C., and Meun, D. H. C., 1968, Kinetics of the photochemical addition of [35S]cysteine to polynucleotides and nucleic acids, Biochemistry 7:1033–1037.
Smith, K. C., and O’Leary, M. E., 1967, Photoinduced DNA-protein crosslinks and bacterial killing: A correlation at low temperature, Science 155:1024–1026.
Smith, K. C., Hodgkins, B., and O’Leary, M. E., 1966, The biological importance of ultraviolet light induced DNA-protein cross-links in Escherichia coli TAU, Biochim. Biophys. Acta 114:1–15.
Sobell, H. N., 1976, Symmetry in nucleic acid structure and its role in protein-nucleic acid interaction, Ann. Rev. Biochem. 45:307–335.
Solage, A., and Cedar, H., 1978, Organization of 5-methylcytosine in chromosomal DNA, Biochemistry 17:2934–2942.
Sperling, J., 1976, Photochemical cross-linking of ATP to histone H4, Photochem. Photobiol. 23:323–326.
Sperling, J. and Havron, A., 1976, Photochemical cross-linking of neighboring residues in protein-nucleic acid complexes: RNase and pyrimidine nucleotide inhibitors, Biochemistry 15:1489–1495.
Sperling, J., and Havron, A., 1977a, Specificity of photochemical cross-linking in protein-nucleic acid complexes, in: Excited States in Organic Chemistry and Biochemistry (B. Pullman and N. Goldblum, eds.), pp. 79–54, D. Reidel, Boston.
Sperling, J., and Havron, A., 1977b, Protein-nucleic acid photo-interaction, Photochem. Photobiol. 26:661–664.
Sperling, J., and Sperling, R., 1978, Photochemical cross-linking of histones to DNA in nucleosomes, Nucleic Acids Res. 5:2755–2773.
Stankunas, A., Rosenthal, I., and Pitts, J. N., Jr., 1971, Photochemical and radiochemical alkylation of caffeine by alkyl amines, Tetrahedron Lett., 4779–4782.
Steinmaus, H., Rosenthal, I., and Elad, D., 1969, Photochemical and 7-ray-induced reactions of purines and purine nucleotides with 2-propanol, J. Amer. Chem. Soc. 91:4921–4923.
Steinmaus, H., Elad, D., and Ben-Ishai, R., 1970, Ultraviolet light-induced purine modified DNA, Biochem. Biophys. Res. Commun. 40:1021–1025.
Steinmaus, H., Rosenthal, I. and Elad D., 1971, Light- and 7-ray-induced reactions of purines and purine nucleosides with alcohols, J.Org. Chem. 36:3594–3598.
Strniste, G. F., and Rail, S. C., 1976, Induction of stable protein-deoxyribonucleic acid adducts in Chinese hamster cell chromatin by ultraviolet light, Biochemistry 15:1712–1719.
Strniste, G. F., and Smith, D. A., 1974, Induction of stable linkage between the deoxyribonucleic acid-dependent ribonucleic acid polymerase and d(A-T) n : d(A-T) n by ultraviolet light, Biochemistry 13:485–493.
Strniste, G. F., Hardin, J. M., and Rall, S. C., 1977, Isolation and characterization of stable protein-DNA adducts induced in chromatin by ultraviolet light, in: Protein Cross-Linking (M. Friedman, ed.), Part A, pp. 571–594, Plenum Press, New York.
Thomas, J. O., 1976, Chemically induced DNA-protein cross-linking, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 193–205, Plenum Press, New York.
Tipton, K. F., 1975, Monamine oxidase, in: Handbook of Physiology (R. O. Greep and E. B. Astwood, eds.), Vol. 6, pp. 677–697, American Physiological Society, Washington, D.C.
Todd, P., and Han, A., 1976, UV-induced DNA to protein cross-linking in mammalian cells, in: Aging, Carcinogenesis and Radiation Biology (K. C. Smith, ed.), pp. 83–104, Plenum Press, New York.
Todd, P., Allen, B. S., and Hardin, J. M., 1974, A search for a nucleoprotein photoproduct in mammalian cells exposed to ultraviolet light, Abstract. Second Annual Meeting of the American Society for Photobiology, Vancouver, 1974, p. 66.
Toder, B. H., Branca, S. J., and Smith, A. B., 1977, Photochemistry of 2(5H)-furanone, Hydrogen abstraction by the β-carbon atom, J. Org. Chem. 42:904–906.
Toth, B., and Dose, K., 1976, Photochemically induced cross-links between DNA and alcohol dehydrogenase or salmine, respectively. Rad. Environ. Biophys. 13:105–113.
Turchinsky, M. F., Broude, N. E., Kusova, K. S., Abdurashidova, G. G., and Budowsky, E. I., 1977, UV-induced formation of RNA-protein cross-linking in 30S subunits of Escherichia coli ribosomes, Bioorg. Khim. 3:1013–1020. (in Russian) [Chem. Abs. 87:147533f (1977)].
Ulmer, E., Mienke, M., Ross, A., Fink, G., and Brimacombe, R., 1978, Chemical cross-linking of protein to RNA within intact ribosomal subunits from Escherichia coli, Molec. Gen. Genet. 160:183–193.
Umansky, S. R., and Domashenko, A. D., 1977, The effect of gamma irradiation on the interaction of DNA with nuclear non-histone proteins, Int. J. Radiat. Biol. 32:361–367.
van der Schans, G. P., van Rijn, C. J. S., and Bleichrodt, J. F., 1976, Binding of radiation-induced phenylalanine radicals to DNA: Influence on the biological activity of the DNA and on its sensitivity to the induction of breaks by 7-rays, Int. J. Radiat. Biol. 29:51–63.
Van Holde, K. E., and Isenberg, I., 1975, Histone interaction and chromatin structure, Acc. Chem. Res. 8:327–335.
Varghese, A. J., 1973a, α-S-cysteinyl-5,6-dihydrothymine: a possible model for radiation-induced cross-linking of DNA and protein, Biochem. Biophys. Res. Commun. 51:858–862.
Varghese, A. J., 1973b, Properties of photoaddition products of thymine and cysteine, Biochemistry 12:2725–2730.
Varghese, A. J., 1974a, Photoaddition products of uracil and cysteine, Biochim. Biophys. Acta 374:109–114.
Varghese, A. J., 1974b, Photochemical addition of glutathione to uracil and thymine, Photochem. Photobiol. 20, 339–343.
Varghese, A. J., 1974c, Photoreaction of 5-bromouracil in the presence of cysteine and glutathione, Photochem. Photobiol. 20:461–464.
Varghese, A. J., 1976, Photochemical addition of amino acids and related compounds to nucleic acid constituents, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 207–223, Plenum Press, New York.
Varghese, A. J., and Rauth, A. M., 1974, Evidence for the addition of sulfhydryl compounds to thymine in UV-irradiated mammalian cells. Abstract Second Annual Meeting of the American Society for Biology, Vancouver, 1974, p. 65.
von Hippel, P. H., and McGhee, J. D., 1972, DNA-protein interactions, Ann. Rev. Biochem. 41:231–300.
Walrant, P., Santus, R., and Charlier, M., 1976, Role of complex formation in the photosensitized degradation of DNA induced by N-formylkynurenine, Photochem. Photobiol. 24:13–19.
Wang, S. Y., 1961, Photochemical reactions in frozen solution, Nature 190:690–693.
Wang, S. Y., 1965, Photochemical reactions of nucleic acid components in frozen solution, Fed. Proc. 24 :S71–S79
Wang, S. Y., 1976, Pyrimidine bimolecular photoproducts, in: Photochemistry and Photobiology of Nucleic Acids (S. Y. Wang, ed.) Vol. 1, pp. 295–356, Academic Press, New York.
Wataya, Y., Negeshi, K., and Hayatsu, H., 1973, Debromination of 5-bromo-2′-deoxyuridine by cysteine. Formation of deoxyuridine and S[5–2′-deoxyuridyl]cysteine, Biochemistry 12:3992–3998.
Weintraub, H., 1973, The assembly of newly replicated DNA into chromatin, Cold Spring Harbor Symp. Quant. Biol. 38:247–256.
Wells, R. D., Blakesley, R. W., Hardies, S. C., Horn, G. T., Larson, J. E., Seising, E., Burd, J. F., Chan, H. W., Dodgson, J. B., and Jensen, K. F., 1977, The role of DNA structure in genetic regulation, CRC Crit. Rev. Biochem. 4:305–340.
Wilkins, R. J., and MacLeod, H. D., 1976, Formaldehyde induced DNA-protein cross-links in Escherichia coli, Mutation Res. 36:11–16.
Williams, G. J. B., Varghese, A. J., and Berman, H. M., 1977, Model compounds for protein-nucleic acid interactions. 5. 5-S-cysteinyluracil monohydrate, a photoaddition product between an amino acid and pyrimidine base, J. Amer. Chem. Soc. 99:3150–3154.
Wu, M., and Davidson, N., 1978, An electron microscopic method for the mapping of proteins attached to nucleic acids. Nucleic Acids Res. 5:2825–2846.
Wu, R., Bahl, C. P., and Narang, S. A., 1978, Lactose operator-repressor interaction, Curr. Top. Cell Regul. 13:138–178.
Yamamoto, O., 1976, Ionizing radiation-induced DNA-protein cross-linking, in: Aging, Carcinogenesis, and Radiation Biology (K. C. Smith, ed.), pp. 165–192, Plenum Press, New York.
Yamane, T., Wyluda, B. J., and Shulman, R. G., 1967, Dihydrothymine from UV-irradiated DNA, Proc. Nat. Acad. Sci. USA 58:439–442.
Yang, N. C., Okazaki, R., and Liu, F. T., 1974, Photosensitized conversion of cytosine into uracil derivatives in presence of mercaptans, J. Chem. Soc. Chem. Commun., 462–463.
Yue, V. T., and Schimmel, P. R., 1977, Direct and specific photochemical cross-linking of adenosine 5’-triphosphate to an aminoacyl-tRNA synthetase, Biochemistry 16:4678–4684.
Zook, D. E., and Fahnestock, S. R., 1978, Covalent cross-linking of ribosomal RNA and proteins by methylene blue-sensitized oxidation, Biochem. Biophys. Acta 517:400–406.
Zwieb, C., and Brimacombe, R., 1978, RNA-protein cross-linking in Escherichia coli, 30S ribosomal subunits: A method for the direct analysis of the RNA region involved in the cross-links, Nucleic Acids Res. 5:1189–1206.
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Shetlar, M.D. (1980). Cross-Linking of Proteins to Nucleic Acids by Ultraviolet Light. In: Smith, K.C. (eds) Photochemical and Photobiological Reviews. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3641-9_4
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