Involvement of Lipids in the Action of Ethanol and Other Anesthetics
While it is generally accepted that ethanol and other anesthetics act on membranes, there is much debate on whether membrane proteins or lipids are involved in their action. The purpose of this paper is to review the evidence which suggests an involvement of lipids. The evidence implicating lipids at the site of action of anesthetics will first be cited. Then the lipid compositional changes responsible for the expression of tolerance will be discussed.
KeywordsLipid Extract Benzyl Alcohol Membrane Fluidity Ethanol Tolerance Membrane Cholesterol
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