Advertisement

Visual Averaged Evoked Responses and Platelet Monoamine Oxidase in Patients Suffering From Alcoholism

  • Lars von Knorring
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 126)

Abstract

In different individuals alcohol abuse may be caused by varying contributions of psychological, social or biological factors. Genetic factors seem to be of etiological importance in some alcoholics. Evidence supporting this view has emerged from studies of children adopted at an early age and raised apart from their alcoholic biological parents (Goodwin et al., 1973, Bohman, 1976). Thus, the study of personality characteristics, especially genetically determined ones, in individuals with alcoholism appears to be a useful approach.

Keywords

Monoamine Oxidase Stimulus Intensity Alcoholic Patient Monoamine Oxidase Activity Neurophysiological Measure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adolfsson, R., Gottfries, C.G., Oreland, L., Roos, B.E., Wiberg, A. and Winblad, B. Monoamine oxidase activity is related to serotoninergic activity in human brain. In preparation.Google Scholar
  2. Bohman, M. Genetic aspects of alcoholism and criminality in the light of an adoption material. Lakartidningen, 73: 2734–2738, 1976.PubMedGoogle Scholar
  3. Buchsbaum, M.S. Neural events and the psychophysical law. Science, 172: 502, 1971.PubMedCrossRefGoogle Scholar
  4. Buchsbaum, M.S. Average evoked response and stimulus intensity in identical and fraternal twins. Physiol. Psychol., 2: 365–370, 1974.CrossRefGoogle Scholar
  5. Buchsbaum, M.S., and Silverman, J. Stimulus intensity control and the cortical evoked response. Psychosom. Med., 30: 12–22, 1968.PubMedGoogle Scholar
  6. Buchsbaiam, M.S., Coursey, R.D. and Murphy, D.L. The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity. Science. 194: 339–341, 1976.CrossRefGoogle Scholar
  7. Buchsbaum, M., Landau, S., Murphy, D. and Goodwin, F. Average evoked response in bipolar and unipolar affective disorders: relationship to sex, age of onset and monoamine oxidase. Biol. Psychiat. 7: 199–212, 1973.Google Scholar
  8. Goodwin, D.W., Schulsinger, F., Hermansen, L., Guze, S.B., and Winokur, G. Alcohol problems in adoptees raised apart from alcoholic biological parents. Arch. Gen. Psychiat., 28: 238–243, 1973.PubMedCrossRefGoogle Scholar
  9. Gottfries, C-G., Oreland, L., Wiberg, A. and Winblad, B. Lowered monoamine oxidase activity in brain from alcoholic suicides. J. Neurochemistry, 25: 667–673, 1975.CrossRefGoogle Scholar
  10. Gottfries, C-G., von Knorring, L. and, Oreland, L. Platelet monoamine oxidase in subgroups of patients with affective psychoses and its relation to suicidal behaviour and lithium treatment. In preparation. Jarvilehto, T., Laalso, M.L. and Virsu, V. Human auditory evoked responses during hangover. Psychopharmacologia, 42: 173–177, 1975.Google Scholar
  11. von Knorring, L. The experience of pain in patients with depressive disorders. A clinical and experimental study. Umea univ. medical dissertations. New series, No. 2, Umea University, 1975.Google Scholar
  12. von Knorring, L. Visual averaged evoked responses in patients suffering from alcoholism. Neuropsychobiology, 2; 233–238, 1976.CrossRefGoogle Scholar
  13. von Knorring, L. Visual averaged evoked responses in patients with bipolar affective disorders. Neuropsychobiology, 5: 314–320, 1978.CrossRefGoogle Scholar
  14. von Knorring, L. and Oreland, L. Visual averaged evoked responses and platelet monoamine oxidase activity as an aid to identify a risk group for alcoholic abuse. A preliminary study. In preparationGoogle Scholar
  15. von Knorring, L., Monakhov, K. and Perris, C. Augmenting/Reducing: an adaptive switch mechanism to cope with incoming signals in healthy subjects and psychiatric patients. Neuropsychobiology, 4: 150–179, 1978.CrossRefGoogle Scholar
  16. von Knorring, L., Almay, B.G.L., Johansson, F., and Terenius, L, Endorphins in CSF in relation to augmenting/reducing response in V.AER. Neuropsychobiology, in press.Google Scholar
  17. Monakhov, K. Concept of functional stratification in investigations of mental and higher nervous activity (in Russian) Zh. vyssh, nerv. Deyzt. I.P. Pavlova 26: 4, 1976.Google Scholar
  18. Nies, A., Robinson, D.S., Lamborn, K.R. and Lampert, R.P, Genetic control of platelet and plasma monoamine oxidase activity. Arch. Gen. Psychiatry, 28: 834–883, 1973.PubMedCrossRefGoogle Scholar
  19. Petrie, A. Individuality in Pain and Suffering. University of Chicago Press, Chicago, (2d Edition). 1978.Google Scholar
  20. Soskis, D.A. and Shagass, C. Evoked potential tests of augmenting/reducing. Psychophysiology, 11: 175–190Google Scholar
  21. Stark, L.H. and Norton, J.C. The relative reliability of average evoked response parameters. Psychophysiology, 11: 600–602, 1974.PubMedCrossRefGoogle Scholar
  22. Wiberg, A., Gottfries, C.G. and Oreland, L. Low plate- monoamine oxidase activity in human alcoholics. Med. Biol. Accept for publ,. 1977.Google Scholar
  23. Zuckerman, M. Manual and research report for the sensation seeking scale (SSS). University of Delaware, March 1975.Google Scholar
  24. Zuckerman, M., Murtaugh, T. and Siegel, J. Sensation seeking and cortical augmenting/reducing. Psychophysiology, 11: 535–543, 1974.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Lars von Knorring
    • 1
  1. 1.Department of PsychiatryUniversity of UmeaSweden

Personalised recommendations