A New Model for Reducing Ethanol Toxicity
As early as 1933, Widmark (Widmark, 1933) reported that when either glycine or alanine was co-administered with ethanol, lowered blood ethanol levels resulted as compared to those achieved when ethanol was administered. (The subjects used were dogs.) He concluded that a stable compound was formed between ethanol and the amino acids and that this accounted for decreased appearance of ethanol in the blood.
KeywordsSchiff Base Depressant Effect Limit Amino Acid Ethanol Metabolism Ethanol Blood Level
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