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Development of Liver Mitochondrial Aldehyde Dehydrogenase Activities in the Foetal and Neonatal Rat

  • Alan A. Horton
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 126)

Abstract

Changes in the activities of a number of enzymes in the mammalian liver during foetal and postnatal development appear to reflect the different physiological needs of the developing animal faced with environmental alteration (Greengard, 1971). A study of the developmental histories of a number of enzymes in the mammalian liver has resulted in the emergence of two important features. One is that the activities of most enzymes studied do not increase steadily over a prolonged period but increase within hours or days to the activity seen in the adult. Secondly, the emergence of new enzymes or the upsurge of enzymes present at low activities is not evenly distributed along the age axis but occurs in clusters. In rat liver three eventful periods have been discerned (Greengard, 1971). One occurs in late foetal life, another on the first day after birth and another in the third postnatal week.

Keywords

Alcohol Dehydrogenase Aldehyde Dehydrogenase Barbituric Acid Postnatal Development Mammalian Liver 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Alan A. Horton
    • 1
  1. 1.Department of BiochemistryUniversity of BirminghamBirmingham B15 2TTEngland

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