Presence and Potential Significance of o-o’-Unsubstituted PCB Isomers and Trace Aroclor® 1248 and 1254 Impurities

  • David L. Stalling
  • James N. Huckine
  • J. D. Petty
Part of the Environmental Science Research book series (ESRH, volume 16)

Abstract

Determination of the potential impact of PCB contamination on aquatic ecosystems is facilitated by information on the toxico-logical significance of specific PCB constituents. In support of this approach, recent studies, (Goldstein et al 1977 and Poland and Glover 1977), indicate that physiological activity associated with the technical PCB mixtures may be largely due to the presence of trace levels of PCB isomers having no o-o’-chlorine substitution. Hepatic enzyme induction from exposure to the most active of these isomers may approach that of the chlorinated-dibenzofurans and -dioxins. Separation and isolation techniques for structurally similar components of Aroclor1/ mixtures are prerequisites for structure-toxicity correlation studies.

Keywords

Largemouth Bass Mass Spectral Analysis Chlorine Substitution Hepatic Enzyme Induction Injector Split Ratio 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Goldstein, J.A., P. Hickman, H. Bergman, J. McKinney, and M. Walker, (1977), Chem.-Biol. Interactions, 69–87, 17.CrossRefGoogle Scholar
  2. Huckins, J.N., D.L. Stalling, and W.A. Smith, (1978), JAOAC, 32–38 32–38, 61.Google Scholar
  3. Jensen, S., and G. Sundström, (1974), AMBIO, 70–76, 3 Google Scholar
  4. Poland, A., and E. Glover, (1977), Mol. Pharmacol., 924–938, 13.Google Scholar
  5. Riedo, F., D. Fritz, G. Tarjan, and E. Kovats, (1976), J. Chromatogr., 63–83, 126.CrossRefGoogle Scholar
  6. Sissons, D., and D. Welti, (1971), J. Chromatogr., 15–32, 60.CrossRefGoogle Scholar
  7. Stalling, D.L., J.N. Huckins, and W.A. Smith, (1978), Patent Application Serial No. 733,500, USDI, Office of the Solicitor, Washington, D.C.Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • David L. Stalling
    • 1
  • James N. Huckine
    • 1
  • J. D. Petty
    • 1
  1. 1.Columbia National Fishery Research LaboratoryColumbiaUSA

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