Fish Tumor Pathology and Aromatic Hydrocarbon Pollution in a Great Lakes Estuary

  • John J. Black
  • Margaret Holmes
  • Paul P. Dymerski
  • William F. Zapisek
Part of the Environmental Science Research book series (ESRH, volume 16)

Abstract

The relationship between polyaromatic hydrocarbon (PAH) contamination of the aquatic environment and its potential as a persistent health hazard for the associated biota has been the subject of recent research in this laboratory and others (Payne et al, 1978; Dunn and Stich, 1976). We report here studies of a waterway contaminated with industrial organic compounds, including PAH; these studies present evidence that the pollution is mutagenic and has a point source. In addition, there is a high incidence of fish tumor pathology in the immediate outflow area.

Keywords

Toxicity HPLC DMSO Hexane Acetonitrile 

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References

  1. Ames, B.N., et al. 1975. Mutation Research 31: 347–364.Google Scholar
  2. Black, J., et al. Bull, of Env. Cont. and Tox. (in press).Google Scholar
  3. Commoner, B., et al. 1976. EPA Report 600/1–76–022 Gov. Print. Off., Wash., D.C.Google Scholar
  4. Dunn, B., and H.F. Stich, 1976. J. Fisheries Research Board of Canada, 13: 2040–2046.Google Scholar
  5. Environmental Protection Agency, Report No. 905/9–74–100.Google Scholar
  6. Kraybill, H.F. 1976. Prog. Exp. Tumor Res. 20: 34.Google Scholar
  7. McCann, J., et al. 1975. PNAS 72: 5135.ADSCrossRefGoogle Scholar
  8. Payne, J.F., et al. 1978. Science 200: 329–330.ADSCrossRefGoogle Scholar
  9. Sonstegard, R.A. 1977. Ann. N.Y. Acad. Sci. 298: 261–269.ADSCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • John J. Black
    • 1
  • Margaret Holmes
    • 1
  • Paul P. Dymerski
    • 2
  • William F. Zapisek
    • 3
  1. 1.Roswell Park Memorial InstituteBuffaloUSA
  2. 2.Division of Laboratories and ResearchNew York State Department of HealthAlbanyUSA
  3. 3.Department of ChemistryCanisius CollegeBuffaloUSA

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