The Central Anticholinergic Syndrome — Etiology, Diagnosis, and Management

  • Richard C. W. Hall
  • Michael K. Popkin
  • Sondra K. Stickney
  • Earl R. Gardner


The potentiation of the anticholinergic effects of one drug by another is frequently overlooked as a cause of acutely developing psychosis. This is not surprising considering that more than 600 drugs with significant anticholinergic properties are currently commercially available (Alpern and Marriot, 1973). This paper defines the central anticholinergic syndrome (CAS), its forms of presentation, etiology, pharmacology, and management.


Anticholinergic Effect Paralytic Ileus Antiparkinsonian Drug Anticholinergic Activity Antiparkinsonian Agent 
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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Richard C. W. Hall
    • 1
  • Michael K. Popkin
    • 1
  • Sondra K. Stickney
    • 1
  • Earl R. Gardner
    • 1
  1. 1.Departments of Psychiatry and MedicineMedical College of WisconsinMilwaukeeUSA

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