Abstract
A series of clinical trials employing the narcotic antagonist, naloxone, administered on a maintenance and on a contingent basis, have indicated that the therapeutic promise of these compounds has not been borne out. Similar investigative experiences appear to be in the process of being reduplicated by the more potent narcotic antagonist naltrexone. These have emphasized the need for treatment approaches which might enhance the patient’s motivation relative to the treatment endeavor. One such possiblity is the structuring of a dramatic treatment experience prior to the initiation of treatment with a narcotic antagonist. For this purpose the use of psychedelic psychotherapy is suggested.
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References
Blumberg, H., Dayton, H.B., George, M. and Rapaport, D.N. 1961. N-allylnoroxymorphine: a potent narcotic antagonist. Fed. Proc. 20: 311.
Blumberg, H. and Dayton, H.B. 1972. Narcotic antagonist studies with EN-161639A (N-cyclopropylmethylnoroxymorphone). In: Fifth International Congress on Pharmacology, San Francisco. Abstracts of volunteer papers.
Fink, M. 1970. Narcotic antagonists in opiate dependence. Science 169: 1005–1006.
Hanlon, T.E. et al. 1977. Narcotic antagonist treatment of addict parolees-the future of an effective approach. Comp. Psych. 18: 211–219.
Kurland, A.A. 1978. Psychiatric Aspects of Drug Dependence. West Palm Beach, Florida. CRC Press, Inc.
Martin, W.F., Gorodetzky, C.W., and McClane, T.K. 1966. An experimental study in the treatment of narcotic addicts with cyclazocine. Clin. Pharmacol. Ther. 7: 455–465.
Martin, W.R., Jasinski, F.P. and Mansky, P.A. 1973. Naltrexone, an antagonist for the treatment of heroin dependence: effects in man. Arch. Gen. Psych. 28: 784–791.
Report of the National Research Council Committee on Clinical Eval-uation of Narcotic Antagonists, 1978. Clinical evaluation of naltrexone treatment of opiate-dependent individuals. Arch. Gen. Psych. 35: 335–340.
Wikler, A. 1974. Opioid Antagonists and Deconditioning in Addiction Treatment. Paper presented at the syposium on drug dependence-treatment and treatment evaluation. Spandia Interna. Symposium. Stockholm, Sweeden.
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© 1981 Plenum Press, New York
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Kurland, A.A. (1981). Narcotic Antagonists and Strategies for Enhancing Their Effectiveness. In: Schecter, A.J. (eds) Drug Dependence and Alcoholism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3614-3_120
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DOI: https://doi.org/10.1007/978-1-4684-3614-3_120
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