Chemotherapy of Addiction — A Pharmacological Perspective
Accompanying the greater use of drugs to treat narcotic addicts has been the development of new drugs for such treatment. It is conceivable that in the near future the therapist will choose from an array of drugs to treat addict patients. Such a situation would be analogous to that with the chemotherapy of infectious diseases. In such a situation, knowledge of the comparative pharmacology of the available drugs is one factor necessary for rational therapy. This presentation will review the pharmacology of the narcotic antagonists in relation to each other and in relation to those narcotic analgesics used as maintenance drugs. This presentation will not review the relative efficacies of the various classes of agents used to treat addicts nor the rationales for choosing among the agents.
KeywordsPartial Agonist Physical Dependence Agonist Effect Narcotic Analgesic Addiction Research
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