The Consequence of a “Consolidation” Period Following Brief Monocular Deprivation in Kittens

  • R. D. Freeman
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 27)


Brief periods of limited visual exposure, such as monocular deprivation, have been reported to cause changes in striate cortex that are accentuated by a delay prior to physiological study. This notion, called “consolidation” in previous work, has been tested in the present study. Four-week-old normally reared kittens were monocularly occluded for brief periods (8 or 24 hours). Extracellular study of striate cortex was undertaken either immediately after occlusion or following a period during which the animals were kept in darkness. Substantial monocular deprivation effects were found in both groups, but the most pronounced changes were observed for the kittens studied immediately after exposure. Therefore, no “consolidation” has been observed. On the contrary, it appears that the period spent in darkness actually diminished the consequences of the monocular deprivation.


Delay Period Striate Cortex Ocular Dominance Monocular Deprivation Optimal Stimulus 


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  1. Agranoff, W. (1974). Biochemical concomitants of the storage of behavioral information. In: Biochemistry of Sensory Functions. L. Jaenicke (ed.). Springer Verlag, Berlin, pp. 597–623.Google Scholar
  2. Agranoff, W. (1976). Learning and memory: approaches to correlating behavioral and biochemical events. In: Basic Neurochemistry, 2d ed. Siegel, Albers, and Agranoff (eds.). Little, Brown, and Co., Boston, pp. 765–784.Google Scholar
  3. Buisseret, P., E. Gary-Bobo, and M. Imbert (1978). Ocular motility and recovery of orientational properties of visual cortical neurones in dark-reared kittens. Nature 272:816–817.PubMedCrossRefGoogle Scholar
  4. Freeman, R. D. (1978). Restricted visuomotor coordination during development in kittens: striate cortex and behavior. Exp. Brain Res. 33:51–63.PubMedCrossRefGoogle Scholar
  5. Hubel, D. H., and T. N. Wiesel (1962). Receptive fields, binocular interaction, and functional architecture in the cat’s visual cortex. J. Physiol. 160:106–154.PubMedGoogle Scholar
  6. Hubel, D. H., and T. N. Wiesel (1970). The period of susceptibility to the physiological effects of unilateral eye closure in kittens. J. Physiol. 206:419–436.PubMedGoogle Scholar
  7. Movshon, J. A., and M. R. Dursteler (1977). Effects of brief periods of unilateral eye closure on the kitten’s visual system. J. Neurophysiol. 40:1255–1265.PubMedGoogle Scholar
  8. Olson, C. R., and R. D. Freeman (1975). Progressive changes in kitten striate cortex during monocular vision. J. Neurophysiol. 38:26–32.PubMedGoogle Scholar
  9. Peck, C. K., and C. Blakemore (1975). Modification of single neurons in the kitten’s visual cortex after brief periods of monocular visual experience. Exp. Brain Res. 22:57:68.PubMedCrossRefGoogle Scholar
  10. Pettigrew, J. D., and L. J. Garey (1974). Selective modification of single neuron properties in the visual cortex of kittens. Brain Res. 66:160–164.CrossRefGoogle Scholar
  11. Schechter, P. B., and E. H. Murphy (1976). Brief monocular visual experience and kitten cortical binocularity. Brain Res. 109:165–168.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • R. D. Freeman
    • 1
  1. 1.School of OptometryUniversity of CaliforniaBerkeleyUSA

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