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Growth and Neurogenesis in Adult Goldfish Retina

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Book cover Developmental Neurobiology of Vision

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 27))

Abstract

Growth continues in adult goldfish. Cell counts and3 H—thymidine radioautography indicate that the brain and retina increase in size in part by the addition of new neurons. The retina of a large, 4-year-old fish (20 cm in length) has about 20,000,000 neurons, whereas in a small (5 cm) fish there are only about 3,000,000 retinal neurons. New cells are produced at the margins of the retina and are added appositionally at rates of up to 20,000 cells/day. Growth-related changes also occur in the older, more central regions of the retina: the eyeball expands, stretching the retina and decreasing the density of its cells. The rods alone maintain a constant density with growth, so that the proportion of rods relative to other retinal neurons increases as the fish grows. Since new rods are added only at the periphery, a shift in the position of rods with respect to their postsynaptic partners is implied. This suggests that synaptic connections may be continually broken and reformed in the functioning adult goldfish retina.

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Authors and Affiliations

  1. Department of Anatomy, The University of Michigan, Ann Arbor, Michigan, USA

    Pamela Raymond Johns

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  1. Pamela Raymond Johns
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Editors and Affiliations

  1. University of California, Berkeley, California, USA

    Ralph D. Freeman

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© 1979 Plenum Press, New York

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Johns, P.R. (1979). Growth and Neurogenesis in Adult Goldfish Retina. In: Freeman, R.D. (eds) Developmental Neurobiology of Vision. NATO Advanced Study Institutes Series, vol 27. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3605-1_30

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  • DOI: https://doi.org/10.1007/978-1-4684-3605-1_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3607-5

  • Online ISBN: 978-1-4684-3605-1

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