In Vitro and in Vivo Parameters of Humoral and Cellular Immunity in an Animal Model for Protein-Calorie Malnutrition
As a result of recent advances in immunology innumerable reports have emerged in the literature on the general field of nutrition-immunocompetence-disease interactions (2). Originally, questions arising from human observations led to animal experimentation much of which yielded often conflicting findings. Although nutritional modulation of the immune response may be an important factor influencing morbidity and mortality associated with a variety of human disease processes, including cancer, the data generated from a large number of pertinent studies in humans and animals have to be interpreted with caution. That is, many components of the immune system have been studied frequently in isolation from other parameters and apparently out of context with other critical environmental and genetic variables which influence the clinical onset and course of many pathologic conditions.
KeywordsTotal Serum Protein Single Radial Immunodiffusion Hemolytic Complement Activity Total Plasma Cortisol Stimulation Ratio
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