Effects of UV Radiation on the Immune System: Consequences for UV Carcinogenesis

  • M. L. Kripke
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 121B)


Since the early 1900’s, UV light has been suspected of being the causative agent for certain types of human skin cancer (1). Clinical and epidemiological data, as well as animal experiments, have provided strong evidence in support of this hypothesis (2). However, recent evidence from animal studies suggests that UV light can, in addition, affect immunologic functions, and that these immunologic perturbations may be important in the pathogenesis of UV light-induced skin cancer.


Spleen Cell Hind Footpad Transient Depression Human Skin Cancer Normal Spleen Cell 
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • M. L. Kripke
    • 1
  1. 1.Cancer Biology ProgramNCI Frederick Cancer Research CenterFrederickUSA

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