A Metabolic Comparison between Human Blood Monocytes and Neutrophils
The two most prominent types of phagocytic cells in the human circulation are the neutrophilic granulocytes and the monocytes. Both cell types are involved in host defense by their ability to move into the tissues to the site of an infection, to bind to foreign material, to ingest it, and to kill living microorganisms. The latter reaction is mediated to a large extent by the formation of toxic oxygen radicals.
KeywordsOxidative Phosphorylation Lactate Production Neutrophilic Granulocyte Anaerobic Glycolysis H202 Recovery
Unable to display preview. Download preview PDF.
- 1.Goldstein, I. M., Roos, D., Kaplan, H. B. and Weissmann, G., J. Clin. Invest., 56 (1975) 1155.Google Scholar
- 2.Johnston, Jr., R. B., Lehneyer, J. E. and Guthrie, L. A., J. Exp. Med., 143 (1976) 1551.Google Scholar
- 3.Kakinuma, K., J. Biochem. (Tokyo), 68 (1970) 177.Google Scholar
- 6.Sagone, Jr., A. L., King, G. W. and Metz, E. N., J. Clin. Invest., 57 (1976) 1352.Google Scholar
- 7.Sbarra, A. J. and Karnovsky, M. L., J. Biol. Chem., 234 (1959) 1355.Google Scholar