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The Role of Leukocyte Extracts and Myeloperoxidase in the Lysis of Staphylococci and the Inhibition of Bacteriolysis by Anionic Polyelectrolytes and by Inflammatory Exudates

  • I. Ginsburg
  • N. Neeman
  • M. Lahav
  • N. Sela
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 121B)

Abstract

Although much is known today about the mechanisms by which leukocytes and their intracellular enzymes kill bacteria very little is known about the biochemical pathways of degradation of the ingested microbiota. It is accepted that soon after the uptake of bacteria by neutrophils (PMNs) and macrophages fusion of lysosomes with the phagosome occurs. This is followed by the intravacuolar discharge of lysosomal agents which lead to the killing and degradation of the intracellular bacteria (2).

Keywords

Chondroitin Sulfate Cationic Protein Inflammatory Exudate Anionic Polyelectrolyte Leukocyte Extract 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • I. Ginsburg
    • 1
  • N. Neeman
    • 1
  • M. Lahav
    • 1
  • N. Sela
    • 1
  1. 1.Department of Oral BiologyHadassah School of Dental Medicine of Hebrew University (Founded by the Alpha Omega Fraternity)JerusalemIsrael

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