UV Photobiology: Excision Repair
In addition to photoreactivation, the reversal of damage produced in DNA by ultraviolet light, there is another repair process, excision, in which the damaged regions are cut out of the DNA. Although we will deal mostly with damage inflicted on DNA by ultraviolet light, there are also excision systems for chemical damage as well. Most of what we know about excision comes from E. coli, but we can extrapolate to mammalian systems; how well the extrapolation fits the actual case is not yet clear.
KeywordsExcision Repair Nucleotide Excision Repair Repair Pathway Xeroderma Pigmentosum Repair Synthesis
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