Time-Resolved Fluorescence Studies on Drug Binding Sites
Fluorescence spectroscopic techniques have been widely used in the past to obtain information about simple lipid bilayers and purified lipid-protein complexes. The same techniques have also been used to study intact biological membranes but the results of such studies have been much more difficult to interpret, simply because the membrane is a highly heterogeneous structure. In general a single composite spectrum is obtained either from all components of the membrane or from probe molecules dissolved in a variety of sites in the membrane when excited with continuous wave radiation.
KeywordsFluorescence Lifetime Fluorescence Decay Microsomal Membrane Dual Exponential Function Intense Light Pulse
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