The Introduction of Missing Enzymes into Human Cells

Alternatives to DNA Recombinancy in Genetic Disease
  • Gerald Weissmann


The hazards and promises of new research have probably never been as carefully anticipated as those arising from studies of DNA recombinance. It is to the solid credit of the discoverers of gene splicing that they themselves have warned us of its possible risks, have convened meetings to discuss the social consequences of its applications, and have been instrumental in elaborating what they perceive to be appropriate guidelines for its safe exploitation. Yet even this responsible, cautious approach has not prevented the emergence of frequently harsh (and occasionally cogent) criticism both from within and without the scientific community. Having gone this far, the critics say, we should perhaps go no further into the business of mucking around with the genomes of man or microbes until we’ve thought a lot more about the whole problem.


Enzyme Deficiency Lysosomal Storage Disease Aberrant Gene Nervous System Damage Genomic Intervention 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Gerald Weissmann
    • 1
  1. 1.Division of RheumatologyNew York University School of MedicineNew YorkUSA

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