How Research on the Cell Biology of Reproduction Can Contribute to the Solution of the Population Problem

  • Don W. Fawcett


Mankind is now confronted by two inseparable problems of awesome magnitude—the uncontrolled growth of the world population and a serious shortage of food for the undernourished millions already born and for the millions yet to be born. The attainment of zero population growth in some regions of this country has led to a regrettable complacency about the population problem. But the fact remains that some 200,000 persons are being added to the world population every day—74 million new mouths to feed every year. The United Nations has identified 43 countries with very low per capita income, inadequate diet, and large food deficits. It is especially distressing that the highest fertility rates are found in many of those same developing countries that are struggling to improve the lot of their people only to find that unchecked population growth is wiping out the gains achieved in agricultural production. Research on the cell biology of reproduction provides the understanding of basic mechanisms that is essential for progress in the limitation of human fertility and in the promotion of fertility in food-producing domestic animals.


Zona Pellucida Cumulus Cell Artificial Insemination Acrosome Reaction Sperm Head 
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  1. Afzelius, B. A., 1976, A human syndrome caused by immotile cilia (Kartagener’s syndrome), Science 193: 317.CrossRefGoogle Scholar
  2. Bloom, W., and Fawcett, D. W., 1975, Textbook of Histology, W. B. Saunders, Philadelphia.Google Scholar
  3. Fawcett, D. W., 1975a, The mammalian spermatozoon, Dev. Biol. 44: 394.CrossRefGoogle Scholar
  4. Fawcett, D. W., 1975b, Gametogenesis in the male: Prospects for its control, in: Developmental Biology of Reproduction ( C. L. Markert and J. Papaconstantinou, eds.) pp. 25–53, Academic Press, New York.Google Scholar
  5. Gibbons, I. R., 1965, Dynein, a protein with ATPase activity from cilia, Science 149: 424.CrossRefGoogle Scholar
  6. Hamilton, W. J. (ed.), 1956, Textbook of Human Anatomy, MacMillan, London.Google Scholar
  7. Mann, T., 1975, Animal reproduction and artificial insemination, Proc. R. Inst. G.B. 48: 107.Google Scholar
  8. Pedersen, H., and Rebbe, H., 1975, Absence of arms in the axoneme of immobile human spermatozoa, Biol. Reprod. 12: 541.CrossRefGoogle Scholar
  9. Polge, C., and Rowson, L. E. A., 1952, Fertilizing capacity of bull spermatozoa after freezing at -79°C, Nature (London) 169: 626.Google Scholar
  10. Satir, P., 1968, Studies on cilia, in. Further studies on the cilium tip and a “sliding-filament” model of ciliary motility, J. Cell Biol. 39: 77.CrossRefGoogle Scholar
  11. Satir, P., 1974, How cilia move, Sci. Am. 231: 44–63.Google Scholar
  12. Smith, A. U., 1961, Biological Effects of Freezing and Supercooling, Edward Arnold, London.Google Scholar
  13. Summers, K. E., and Gibbons, I. R., 1971, Adenosine triphosphate induced sliding of tubules in trypsin treated flagella of sea-urchin sperm, Proc. Natl Acad. Sci. USA 68: 3092.CrossRefGoogle Scholar
  14. Wilmut, I., and Rowson, L. E. A., 1973, Experiments on the low temperature preservation of cow embryos, Vet. Rec. 92: 686 - 690.CrossRefGoogle Scholar
  15. Yanigamachi, R., 1973, Behavior and functions of the structural elements of the mammalian sperm head in fertilization, in: Regulation of Mammalian Reproduction: Proceedings ( S. J. Segal, R. Crozier, P. A. Corfman, and P. G. Condliffe, eds.), National Institutes of Health Conference, Charles C Thomas, Springfield, I II.Google Scholar

Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Don W. Fawcett
    • 1
  1. 1.Harvard University Medical SchoolCambridgeUSA

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