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Cannabinols

  • Marc A. Schuckit
Part of the Critical Issues in Psychiatry book series (CIPS)

Abstract

Marijuana is second only to alcohol as the most widely used of the drugs described in this text. The health care problems involved with delta-9-tetrahydrocannabinol, or THC (the most active ingredient in marijuana and hashish) include panic reactions, toxic reactions, and a great deal of anxiety in the general population about possible mental and physiological damage to young users. Because, as health care deliverers, you will be called upon to give information about this drug to worried parents and to teenagers attempting to make decisions about future use, this chapter presents information on the history, physiology, and medical effects of the cannabinols.

Keywords

Cannabis Usage Toxic Reaction Marijuana Smoker Mild Level Young User 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Jaffe, J. H. Drug addiction and drug abuse. In L. S. Goodman & A. Gilman (Eds.), The Pharmacological Basis of Therapeutics, 5th Ed. New York: Macmillan, 1975, pp. 284–324.Google Scholar
  2. 2.
    Liskow, B. Marijuana deterioration. Journal of the American Medical Association. 214: 1709, Nov. 30, 1970.Google Scholar
  3. 3.
    Talbott, J. A. The emergency management of marijuana psychosis. In P. G. Boume (Ed.), A Treatment Manual for Acute Drug Abuse Emergencies. Washington, D.C.: U.S. Government Printing Office, 1974, pp. 83–87.Google Scholar
  4. 4.
    Nahas, G. Biomedical aspects of cannabis usage. Bulletin on Narcotics. 24 (2): 13–27, 1977.Google Scholar
  5. 5.
    Lemberger, L., & Rubin, A. The physiologic disposition of marihuana in man. Life Sciences. 17: 1637–1642, 1975.PubMedCrossRefGoogle Scholar
  6. 6.
    Stillman, R., Galanter, M., & Lemberger, L. Tetrahydrocannabinol (THC): Metabolism and subjective effects. Life Sciences. 19: 569–576, 1976.PubMedCrossRefGoogle Scholar
  7. 7.
    Mendelson, J. H., Rossi, A. M., & Meyer, R. E. The Use of Marihuana: A Psychological and Physiological Inquiry. New York: Plenum Press, 1974.CrossRefGoogle Scholar
  8. 8.
    Secretary of Health, Education, and Welfare. Marijuana and Health. Sixth Annual Report to the U.S. Congress. Rockville, Md.: National Institute on Drug Abuse, 1976.Google Scholar
  9. 9.
    Galanter, M., Stillman, R., Wyatt, R. J., et al. Marihuana and Social Behavior. A controlled study. Archives of General Psychiatry. 30: 518–521, 1974.CrossRefGoogle Scholar
  10. 10.
    Weil, A. T., Zinberg, N. E., & Nelsen, J. M. Clinical and psychological effects of marihuana in man. Science. 162: 1234–1242, 1968.PubMedCrossRefGoogle Scholar
  11. 11.
    Weil, A. T. Adverse reactions to marihuana. Classification and suggested treatment. New England Journal of Medicine. 282 (18): 997–1000, 1970.Google Scholar
  12. 12.
    Feeney, D. M. Marihuana and epilepsy. Science. 197: 1301–1302, 1977.PubMedGoogle Scholar
  13. 13.
    Cohen, S., & Stillman, R. C. The Therapeutic Potential of Marihuana. New York: Plenum Medical Book Company, 1976.CrossRefGoogle Scholar
  14. 14.
    Gottschalk, L. A., Aronow, W. S., & Prakash, R. Effect of marijuana and placebo–marijuana smoking of psychological state and on psychophysiological cardiovascular functioning in anginal patients. Biological Psychiatry. 12 (2): 255–266, 1977.PubMedGoogle Scholar
  15. 15.
    Kaymakcalan, S. Potential dangers of cannabis. International Journal of the Addictions. 10 (14): 721–735, 1975.Google Scholar
  16. 16.
    Cohen, S. Marihuana: Does it have medical usefulness? Drug Abuse and Alcoholism Newsletter. 5 (10), 1976.Google Scholar
  17. 17.
    Halikas, J. A., Goodwin, D. W., & Guze, S. B. Marihuana use and psychiatric illness. Archives of General Psychiatry. 27: 162–165, 1972.PubMedCrossRefGoogle Scholar
  18. 18.
    Hepler, R. S., & Petrus, R. Experiences with administration of marihuana to glaucoma patients. In S. Cohen & R. C. Stillman (Eds.), The Therapeutic Potential of Marihuana. New York: Plenum Medical Book Company, 1976, pp. 63–76.CrossRefGoogle Scholar
  19. 19.
    Treffert, D. A. Marihuana use in schizophrenia: A clear hazard. Presented at the 130th Annual Meeting of the American Psychiatric Assocation, Toronto, Ontario, Canada, May 5, 1977.Google Scholar
  20. 20.
    Pillard, R. C. Marihuana. New England Journal of Medicine. 283 (6): 292–304, 1970.CrossRefGoogle Scholar
  21. 21.
    Naditch, M. P. Acute adverse reactions to psychoactive drugs. Journal of Abnormal Psychology. 83: 394–403, 1974.PubMedCrossRefGoogle Scholar
  22. 22.
    Halikas, J. A. Marijuana use and psychiatric illness. In L. L. Miller (Ed.), Marijuana: Effects on Human Behavior. New York: Academic Press, 1974, pp. 265–302.Google Scholar
  23. 23.
    Ablon, S. L., & Goodwin, F. K. High frequency of dysphoric reactions of tetrahydrocannabinol among depressed patients. American Journal of Psychiatry. 131 (4): 448–453, 1974.PubMedGoogle Scholar
  24. 24.
    Kolansky, H., & Moore, W. T. Marihuana, can it hurt you? Journal of the American Medical Association. 232 (9): 923–924, 1975.PubMedCrossRefGoogle Scholar
  25. 25.
    Brill, N. Q., & Christie, R. L. Marihuana use and psychosocial adaptation. Follow–up study of a collegiate population. Archives of General Psychiatry. 31: 713–719, 1974.Google Scholar
  26. 26.
    Woodruff, R. A., Goodwin, D. W., & Guze, S. B. Psychiatric Diagnosis. New York: Oxford University Press, 1974.Google Scholar
  27. 27.
    Meyer, R. E. Psychiatric consequences of marijuana use. In J. R. Tinklenberg (Ed.), Marijuana and Health Hazards. New York: Academic Press, 1975, pp. 133–152.Google Scholar
  28. 28.
    Campbell, A. M. G., Evans, M., Thomason, J. L. G., et al. Cerebral atrophy in young canabis smokers. Lancet II: 1219–1224, 1971.CrossRefGoogle Scholar
  29. 29.
    Grant, I., & Mohns, L. Chronic cerebral effects of alcohol and drug abuse. International Journal of the Addictions. 10 (5): 883–920, 1975.PubMedGoogle Scholar
  30. 30.
    Stefanis, C., Laikos, A., Boulougouris, J., et al. Chronic hashish use and mental disorder. American Journal of Psychiatry. 133 (2): 225–227, 1976.PubMedGoogle Scholar
  31. 31.
    Liskow, B., Liss, J. L., & Parker, C. W. Allergy to marihuana. Annals of Internal Medicine. 75: 571–574, 1971.PubMedGoogle Scholar
  32. 32.
    Bier, M. M., & Steahly, L. P. Emergency treatment of marihuana complicating diabetes. In P. G. Boume (Ed.), A Treatment Manual for Acute Drug Abuse Emergencies. Washington, D.C.: U.S. Government Printing Office, 1974, pp. 88–94.Google Scholar
  33. 33.
    Janowsky, D. S., Meacham, M. P., Blaine, J. D., et al. Simulated flying performance after marihuana intoxication. Aviation, Space, and Environmental Medicine. Feb. 1976, pp. 124–128.Google Scholar
  34. 34.
    Kandel, D. Stages in adolescent involvement in drug use. Science. 190: 912–914, 1975.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • Marc A. Schuckit
    • 1
  1. 1.San Diego Veterans Administration Medical Center, School of MedicineUniversity of CaliforniaSan DiegoUSA

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