Advertisement

Event Related Potential Research in Psychiatry

  • Walton T. Roth
  • Judith M. Ford
  • Adolf Pfefferbaum
  • Thomas B. Horvath
  • Carol M. Doyle
  • Bert S. Kopell
Part of the NATO Conference Series book series (NATOCS, volume 9)

Abstract

Over the last few years our laboratory has applied event related potential (ERP) techniques in three main research areas: psychopathology, normal aging and drugs of abuse. In this research we have used a variety of paradigms eliciting a variety of ERP components. It is a matter of efficiency to administer a battery of paradigms to subjects from populations that are difficult to select and recruit. The paradigms in a battery are chosen to elicit ERP components at various recording sites and latencies, and which reflect various stages and types of brain activity.

Keywords

Event Related Potential Contingent Negative Variation Noise Burst Warning Tone Sustained Potential 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Anders, T.R. and Fozard, J.L. Effects of age upon retrieval from primary and secondary memoryDevelop Psychol,1973,9411–416.CrossRefGoogle Scholar
  2. Dubrovsky, B. and Dongier, M. Evaluation of event related potentials in selected groups of psychiatric patients. In W.C. McCallum and J.R. Knott (Eds.),The Responsive Brain, Bristol: John Wright, 1976.Google Scholar
  3. Floris, V., Morocutti, G., Amabile, G., Bernardi, G. and Rizzo, P. Recovery cycle of visual evoked potentials in normal, schizophrenics and neurotic patients. In N.S. Kline and E. Laska (Eds.),Computers and Electronic Devices in Psychiatry, New York: Grune and Stratton, 1968.Google Scholar
  4. Ford, J.M., Roth, W.T., Kopell, B.S. and Dirks, S.J. Evoked response correlates of signal recognition between and within modalitiesScience, 1973,181, 465–466.PubMedCrossRefGoogle Scholar
  5. Ford, J.M., Roth, W.T. and Kopell, B.S. Auditory evoked potentials to unpredictable shifts in pitchPsychophysiol. 1976a13, 32–39.CrossRefGoogle Scholar
  6. Ford, J.M., Roth, W.T. and Kopell, B.S. Attention effects on auditory evoked potentials to infrequent eventsBiol. Psychol., 1976b,4, 65–67.PubMedCrossRefGoogle Scholar
  7. Ford, J.M., Hopkins, W.F. III, Roth W.T., Pfefferbaum, A. and Kopell, B.S. Age effects on event related potentials in a selective attention task. Submitted for publication.Google Scholar
  8. Ford, J.M., Roth W.T., Mohs, R.C. Hopkins, W.F. Ill and Kopell, B.S. The effects of age on event related potentials in a memory retrieval task. Submitted for publication.Google Scholar
  9. Goodin, D.S., Squires, K.C. and Starr, A. Long latency event related components of the auditory evoked potential in dementia. Brain, in press.Google Scholar
  10. Hillyard, S.A., Hink, R.F., Schwent, V.L. and Picton, T.W. Electrical signs of selective attention in the human brainScience, 1973,182, 177–180.PubMedCrossRefGoogle Scholar
  11. Hink, R.F., Fenton, W.H. Jr., Tinklenberg, J.R., Pfefferbaum, A. and Kopell, B.S. Vigilance and human attention under conditions of methylphenidate and secobarbital intoxication: An assessment using brain potentialsPsychophysiol, 1978,15, 116–125.CrossRefGoogle Scholar
  12. Kutas, M. McCarthy, G. and Donchin, E. Augmenting mental chrono- metry: The P300 as a measure of stimulus evaluation timeScience, 1977,197792–795.PubMedCrossRefGoogle Scholar
  13. Levit, A.L., Sutton, S. and Zubin, J. Evoked potential correlates of information processing in psychiatric patientsPsychol. Med, 1973,3, 487–494.PubMedCrossRefGoogle Scholar
  14. Pfefferbaum, A., Ford, J.M., Roth, W.T., Hopkins W.F, III and Kopell, B.S. Event related potential changes in healthy aged females. Electroenceph. Clin. Neurophysiol., in press.Google Scholar
  15. Pfefferbaum, A., Roth, W.T., Tinklenberg, J.R., Rosenbloom, M.S. and Kopell, B.S. The effects of ethanol and meperidine on auditory evoked potentials. Submitted for publication.Google Scholar
  16. Pfefferbaum, A., Horvath, T.B., Roth, W.T., Clifford, S.T. andGoogle Scholar
  17. Kopell, B.S. The effects of chronic alcoholism on the late event related potentials. Presented at Fourth Bienniel International Symposium on Biomedical Research in Alcohol, Zurich, Switzerland, June 1978c.Google Scholar
  18. Roth, W.T. Auditory evoked responses to unpredictable stimuliPsychophysiol., 1973,10125–138.CrossRefGoogle Scholar
  19. Roth, W.T. and Cannon E.H. Some features of the auditory evoked response in schizophrenicsArch Gen Psychiat., 1972,27, 466–471.PubMedCrossRefGoogle Scholar
  20. Roth, W.T., Kopell, B.S., Tinklenberg, J.R., Darley, C.F., Sikora, R. and Vesecky, T.B. The contingent negative variation during a memory retrieval taskElectroenceph Clin Neurophysiol., 1975,38171–174.Google Scholar
  21. Roth, W.T., Ford, J.M., Lewis, S.J. and Kopell, B.S. Effects of stimulus probability and task relevance on event related potentialsPsychophysiol., 1976a,13, 311–317.CrossRefGoogle Scholar
  22. Roth, W.T., Krainz, P.L., Ford, J.M., Tinklenberg, J.R., Rothbart, R.M. and Kopell, B.S. Parameters of temporal recovery of the human auditory evoked potentialElectroenceph Clin. Neurophysiol., 1976a,40, 623–632.PubMedCrossRefGoogle Scholar
  23. Roth W.T., Tinklenberg, J.R. and Kopell, B.S. Ethanol and marijuana effects on event related potentials in a memory retrieval paradigmElectroenceph,Clin Neurophysiol., 1977,42, 381–388.CrossRefGoogle Scholar
  24. Roth, W.T., Horvath, T.B., Pfefferbaiam, A., Tinklenberg, J.R.,Mezzich, J.R. andKopell, B.S. Late event related potentialsand schizophrenia. In H. Begleiter (Ed.), Evoked Brain Potentials and Behavior, New York: PleniJin, in press.Google Scholar
  25. Roth, W.T., Rothbart, R.M. and Kopell, B.S. The timing of CNV resolution in a memory retrieval task. Biol. Psychol., 1978b,639–49.PubMedCrossRefGoogle Scholar
  26. Roth, W.T., Ford, J.M. and Kopell, B.S. Long latency evoked potentials and reaction time. Psychophysiol., 1978c,15 17–23.CrossRefGoogle Scholar
  27. Roth, W.T., Pfefferbaum, A., Ford, J.M. and Kopell, B.S. Effects of ethanol on human evoked potentials, in prep.Google Scholar
  28. Ruchkin, D.S. and Sutton, S. Equivocation and P300 amplitude. In D.A. Otto (Ed.), MuItidisciplinary Perspectives in Event Related Brain Potential Research, Washington, D.C.: U.S. Government Printing Office, in press.Google Scholar
  29. Schwent, V.L., Hillyard, S.A. and Galambos, R. Selective attention and the auditory vertex potential. I: Effects of stimulus delivery rateElectroenceph Clin. Neurophysiol., 1976a,40, 604–614.PubMedCrossRefGoogle Scholar
  30. Schwent, V.L., Hillyard, S.A. and Galambos, R. Selective attention and the auditory vertex potential. II: Effects of signal intensity and masking noiseElectroenceph Clin Neurophysiol., 1976b,40, 615–622.PubMedCrossRefGoogle Scholar
  31. Shagass, CEvoked Brain Potentials in Psychiatry, New York: Plenum Press, 1975.Google Scholar
  32. Shagass, C., Straumanis, J.J., Roemer, R.A. and Amadeo, M. Evoked potentials of schizophrenics in several sensory modalitiesBiol. Psychiat., 1977,12221–235.Google Scholar
  33. Shagass, C., Roemer, R.A., Straumanis, J.J. andAmadeo, M. Evoked potential correlates of psychosisBiol. Psychiat., 1978,13, 163–184.PubMedGoogle Scholar
  34. Speck, L. Dim, B. and Mercer, M. Visual evoked responses of psychiatric patientsArch. Gen Psychiat., 1966,15359–63.CrossRefGoogle Scholar
  35. Sternberg, S. High speed scanning in human memoiry. Science 1966,153, 652–654.PubMedCrossRefGoogle Scholar
  36. Timsit-Berthier, M., Delaunoy, J., Koninckx, N. and Rousseau, J.C. Slow potential changes in psychiatry. I. Contingent negative variationElectroenceph. Clin. Neurophysiol., 1973,35. 355–361.PubMedCrossRefGoogle Scholar
  37. Verleger, R. and Cohen, R. Effects of certainty, modality shifts, and guess outcome on evoked potentials and reaction times in chronic schizophrenicsPsychol, Med,, 1978,8: 81–93.CrossRefGoogle Scholar
  38. Woody, C.D. Characterization of an adaptive filter for the analysis of variable latency neuroelectric signalsMed. Biol. Eng., 19675539–553.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Walton T. Roth
    • 1
  • Judith M. Ford
    • 1
  • Adolf Pfefferbaum
    • 1
  • Thomas B. Horvath
    • 1
  • Carol M. Doyle
    • 1
  • Bert S. Kopell
  1. 1.Stanford University School of MedicineStanfordUSA

Personalised recommendations