Age Determinants in Neonatal Primates: A Comparison of Growth Factors

  • M. Michejda
  • W. T. Watson
Part of the Advances in Primatology book series (AIPR)


Interest in nonhuman primates as animal models for biomedical research can be traced back four decades, when rhesus macaques (Macaca mulatta) were used for the first time at Yale University in studies of developmental and reproductive physiology (Hartman, 1932; van Wagenen, 1972). During many years of using nonhuman primates in various areas of biomedical research, an alarming decrease in the wild population of various species has been observed. Thus, the increasing demand for nonhuman primates resulted in the development of large breeding programs and increasing emphasis on domestic breeding rather than importation of various species. However, this requires more information on neonatal care as well as on the early developmental stages of these species in order to raise healthy primates in captivity. The purpose of our study was to contribute to the better understanding of various problems related to the neonatal stage of development in nonhuman primates by obtaining information on growth and development as well as age characteristics and age determination of neonatal M. mulatta. Further, we sought to establish criteria for the best determination of age and its related growth changes in neonates and infants, and to correlate certain growth characteristics with age. Finally, we compared various methods of age determination commonly used in biomedical research to determine which of these is best for the period from birth to 6 months of age.


Rhesus Monkey Nonhuman Primate Rhesus Macaque Postnatal Life Ossification Center 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • M. Michejda
    • 1
  • W. T. Watson
    • 1
  1. 1.Primate Research Unit Veterinary Resources Branch Division of Research ServicesNational Institutes of HealthBethesdaUSA

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