Follicular Determinants of Corpus Luteum Function in the Human Ovary

  • Kenneth P. McNatty
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 112)


The corpus luteum is a direct continuation of follicle development. It forms after ovulation from the haemorrhagic tissues of the ruptured follicle and it becomes the major source of progesterone circulating in plasma. The main site of progesterone synthesis in the human corpus luteum is presumed to be the granulosa-lutein cells: these cells secrete appreciable amounts of progesterone in tissue culture (~6 pg/cell/day) (1) and they are the most numerous of the various cell-types present.


Granulosa Cell Corpus Luteum Follicular Phase Antral Follicle Human Ovary 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Kenneth P. McNatty
    • 1
  1. 1.Laboratory of Human Reproduction and Reproductive BiologyHarvard Medical SchoolBostonUSA

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