Inhibition by Follicular Fluid of Luteinizing Hormone-Sensitive Adenylate Cyclase in Ovarian Plasma Membranes

  • A. Amsterdam
  • M. Shemesh
  • Y. Salomon
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 112)


The regulation of ovarian function by luteinizing hormone (LH) is mediated by a hormone-sensitive adenylate cyclase (AC). The respective hormone receptors are located on the outersurface of the cell membrane of the follicular cells (for review see ref. 1). Since hormone binding takes place in the extracellular milieu, one should consider the possibility that extracellular factors may affect hormone-receptor interactions and consequently influence the cellular response to the hormone.


Luteinizing Hormone Adenylate Cyclase Follicular Fluid Adenylate Cyclase Activity Follicular Maturation 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • A. Amsterdam
    • 1
  • M. Shemesh
    • 2
  • Y. Salomon
    • 1
  1. 1.Department of Hormone ResearchThe Weizmann Institute of ScienceRehovotIsrael
  2. 2.Kimeron Veterinary Institute Beit-DaganIsrael

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