Estrogen Inhibits Porcine Thecal Androgen Production in vitro

  • P. C. K. Leung
  • B. K. Tsang
  • D. T. Armstrong
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 112)


The importance of the pituitary gonadotropins in the regulation of ovarian steroidogenesis has long been recognized (1,2). Recently, we have reported an inhibitory action of estradiol-17β on luteinizing hormone (LH)-induced ovarian androgen levels in vivo,and suggested that this may be the result of an intra-ovarian feedback regulation by estrogen of its own production (3). The present communication extends this proposal to porcine thecal androgen production in vitro.


Luteinizing Hormone Granulosa Cell Androgen Production Progesterone Production Thecal Cell 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • P. C. K. Leung
    • 1
  • B. K. Tsang
    • 1
  • D. T. Armstrong
    • 1
  1. 1.Departments of Physiology and of Obstetrics & GynaecologyUniversity of Western OntarioLondonCanada

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