Eukaryotic Translation Factors and RNA-Binding Proteins

  • L. P. Ovchinnikov
  • T. N. Vlasik
  • S. P. Domogatsky
  • T. A. Seryakova
  • A. S. Spirin


Messenger RNA in animal (1–5), higher plant (5,6) and lower eukaryotic (7) cells is always complexed with protein and exists in the form of ribonucleoprotein particles with an RNA to protein weight ratig of 1 to 3 (buoyant density in CsC1 is about 1.4 g/cm3). The term “informosomes” was suggested to denote this type of particles (1,2). Three classes of such particles are distinguished: nuclear ribonucleoproteins (8–10), free cytoplasmic informosomes (1–5) and polyribosomal messenger ribonucleoproteins (11–13). A hypothesis was proposed that informosomal proteins can serve for the transport of mRNA from the nucleus to the cytoplasm (1,2,9), for the stabilization and protection of mRNA in the cell (2) and for regulation of protein biosynthesis (1,2,4).


Elongation Factor Buoyant Density Translation Factor FEBS Letter Wheat Embryo 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • L. P. Ovchinnikov
    • 1
  • T. N. Vlasik
    • 1
  • S. P. Domogatsky
    • 1
  • T. A. Seryakova
    • 1
  • A. S. Spirin
    • 1
  1. 1.Institute of Protein ResearchAcademy of Sciences of the USSRMoscow RegionUSSR

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