Abstract
Only two types of organization of the structural genes in the eukaryotes have been known until recently. Most of the genes are represented by unique sequences occurring one per genome. The genes for globins, ovalbumin, fibroin, albumin, crystallins and many other can be mentioned as examples. It is suggested that unique genes are surrounded by DNA sequences which do not encode any protein but may participate in the regulation of expression of the particular gene. It was found with D.melanogaster that one band in a polytene chromosome containing about 20–30 kb per single DNA strand on the average corresponds approximately to one gene or, more precisely, to one complementation group. This indicates the existence of excess DNA in a genome which may be involved in regulation and other service functions. The location of unique genes along the chromosome is strictly fixed.
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References
Y.V. Ilyin, N.A. Tchurikov, G.P. Georgiev, Selection and some properties of recombinant clones lambda bacteriophage containing genes of Droso hila melanogaster, Nucleic Acids Res. 3, 2 5–2 27 (1976).
G.P. Georgiev, Yu.V. Ilyin, A.P. Ryskov, N.A. Tchurikov, G.N. Yenikolopov, V.A. Gvozdev, E.V. Ananiev, Isolation of eukaryotic DNA fragments containing structural genes and the adjacent sequences, Science 195, 394–397 (1977).
Y.V. Ilyin, E.V. Ananiev, A.P. Ryskov, G.N. Yenikolopov, S.A. Limborska, N.E. Maleeva, V.A. Gvozdev, G.P. Georgiev, Studies on the DNA fragments of mammals and Drosophila containing structural genes and adjacent sequences, Cold Spring Harbor Symp. Quant. Biol. 42 (1977) in press.
N.A. Tchurikov, Yu.V. Ilyin, E.V. Ananiev, L.G. Polukarova and G.P. Georgiev, The properties of gene Dm 225, a representative of dispersed repetitive genes in Drosophila melanogaster, Nucleic Acids Res. (1978) in press.
E.V. Ananiev, V.A. Gvozdev, Yu.V.Ilyin, N.A. Tchurikov and G.P.Georgiev, Reiterated genes with variable location in intercalary heterochromatin of D.melanogaster chromosomes, Chromosoma (1978) in press.
D.J. Finnegan, G.M. Rubin, M. Young and D.S. Hogness, Multigene families in the genome of Droso bila melanoí aster, Cold Spring Harbor Symp. Quant. Biol. 2 1971) in press.
R.V. Old, H.G. Kallan, K.W. Gros, Localization of histone gene transcripts in newt lampbrush chromosomes by in situ hybridization, J. Cell Sci. 27, 57–79 (1977).
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© 1979 Plenum Press, New York
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Georgiev, G.P., Ilyin, Y.V., Tchurikov, N.A., Gvozdev, V.A., Ananiev, E.V. (1979). A Novel Type of Gene Organization in Eukaryotic Chromosomes. In: Salvatore, F., Marino, G., Volpe, P. (eds) Macromolecules in the Functioning Cell. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3465-1_6
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DOI: https://doi.org/10.1007/978-1-4684-3465-1_6
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