Organization of Lac Repressor, RNA Polymerase and Histones of DNA

  • A. Mirzabekov
  • R. Beabealashvilli
  • A. Kolchinsky
  • A. Melnikova
  • V. Schick
  • A. Belyavsky


Most of DNA in the eukaryotic genome appears to be complexed with histones. Little is known about the state of DNA in the course of its replication, transcription, and recognition by specific proteins. It may be asked whether DNA remains bound to histones during these processes or histones are displaced from DNA and, in particular, whether DNA covered with histones can be recognized by proteins within its major and minor grooves.


Minor Groove Major Groove Dimethyl Sulfate Nucleosome Core Particle Histone Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • A. Mirzabekov
    • 1
  • R. Beabealashvilli
    • 1
  • A. Kolchinsky
    • 1
  • A. Melnikova
    • 1
  • V. Schick
    • 1
  • A. Belyavsky
    • 1
  1. 1.Institute of Molecular BiologyAçacemy of Sciences of USSRMoscowUSSR

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