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On the Principles of Nucleic Acid — Protein Interaction

  • W. A. Engelhardt

Abstract

The difficulty of establishing recognition bet­ween partners with different molecular “languages”, proteins and nucleic acids is by-passed by two mecha­nisms, in which the principle of coupling factors of opposite character, unity and diversity, integrated in one single molecular structure is operative. For free aminoacids it is the adaptor mechanism, the anti-codon of tRNA playing a dual role. In the protein-DNA interaction hydrogen bonds are established with the components of the common, ever-repeating peptide bond. A kind of “recognition code” can be formulated.

Keywords

Peptide Bond Minor Groove tRNA Molecule Polynucleotide Chain Recognition Code 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • W. A. Engelhardt
    • 1
  1. 1.Institute of Molecular BiologyAcademy of Sciences of the USSRMoscowUSSR

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