Adenovirus Structural Proteins

  • Harold S. Ginsberg
Part of the Comprehensive Virology book series (CV)


Eons ago a wise man might have asked: Can there evolve for study a poisonous, infectious particle, to be termed a “virus,” having the following characteristics: (1) it should be architecturally developed to provide a stable structure; (2) it should be easily propagated and obtainable in large quantities; and (3) its subunits should be readily isolated in native form? Adenoviruses appear to provide one example of an evolutionary triumph that yields a solution to the problem posed. Adenovirus icosahedral structure furnishes nature’s representation of the architects’ presentation of the most stable geometric sphere; adenoviruses are easily propagated and many species can be readily isolated and purified in their native state.


Polypeptide Chain Antigenic Determinant Protein IlIa Sedimentation Coefficient Soluble Antigen 
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Copyright information

© Springer Science+Business Media New York 1979

Authors and Affiliations

  • Harold S. Ginsberg
    • 1
  1. 1.Columbia University College of Physicians and SurgeonsNew YorkUSA

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