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DNA Sequencing of Viral Genomes

  • Gillian M. Air
Part of the Comprehensive Virology book series (CV)

Abstract

In his book Biochemistry Lehninger (1970) illustrated the complexity of the genetic material by devoting a full page to closely spaced arrays of A, G, C, and T letters, calling this “an imaginary base sequence for the chromosome of bacteriophage øX174” and pointing out that this is one of the smallest DNA genomes known. There has been a remarkable revolution in DNA sequencing technology since that page was composed. Not only has the real nucleotide sequence of øX174 been published (Sanger et al., 1977 a), but also DNA sequences of bacteriophages G4 (Godson et al., 1978) and fd (Schaller et al., 1978) and an animal virus, SV40 (Reddy et al., 1978a; Fiers et al., 1978) are completed, or nearly so, and a remarkable array of DNA sequences from various sources is fast accumulating.

Keywords

Coat Protein Simian Virus Nucleotide Pair Late mRNA SV40 Genome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1979

Authors and Affiliations

  • Gillian M. Air
    • 1
  1. 1.Department of MicrobiologyThe John Curtin School of Medical Research Australian National UniversityCanberraAustralia

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