Fetal Cells in the Maternal Circulation
Since the development of new, accurate methods for the detection of chromosome abnormalities and sensitive techniques for diagnosis of biochemical disorders, the whole field of prenatal diagnosis has come into a completely new light. Amniocentesis is nowadays carried out as a routine procedure in most major medical centers throughout the world, and the risks of complications associated with the procedure seem to be very low (see Chapter 2).
KeywordsPrenatal Diagnosis Maternal Blood Fetal Cell Maternal Circulation Primiparous Mother
Unable to display preview. Download preview PDF.
- Jan, W. H., and Herzenberg, L. A., 1973, Fetal RhD+ erythrocytes detected in maternal RhD" blood by electronic fluorescent cell sorter, manuscript.Google Scholar
- Milunsky, A., 1973, Amniocentesis, amniotic fluid and cell culture, in: The Prenatal Diagnosis of Hereditary Disorders, pp. 3–20, Thomas, Springfield, Ill.Google Scholar
- Siebers, J. W., Knauf, I., Hillemanns, H. G., et al., 1975, Antenatal sex determination in blood from pregnant women, Humangenstik 28:273.Google Scholar
- Thorsby, E., and Bratlie, A. 1970, A rapid method for preparation of pure lymphocyte suspensions, in: Histocompatibility Testing (P. J. Terasaki, ed.), pp. 655–656, Munksgaard, Copenhagen.Google Scholar
- Wintrobe, M. M., 1967, The leukocytes, in: Clinical Hematology (M. M. Wintrobe, ed.), pp. 224- 294, Lea & Febiger, Philadelphia.Google Scholar
- Zimmerman, A., and Schmickel, R., 1971, Fluorescent bodies in maternal circulation. Lancet 1:1305.Google Scholar