As outlined in the previous chapter, we sought to develop a research strategy that could be used to assess the utility of narcotic antagonists in the treatment of opiate addiction. The studies involved heroin self-administration in the research ward setting under blocked (with naltrexone) and unblocked conditions. The designs were also intended to facilitate the correlation of behavioral observations with psychological, social, and physiological data obtained on the research ward and interpreted within a multidisciplinary framework.
KeywordsOpiate Addiction Opiate User Narcotic Antagonist Heroin Injection Prospective Subject
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