The Study of Heroin Use in Human Subjects

  • Steven M. Mirin
  • Roger E. Meyer


As outlined in the previous chapter, we sought to develop a research strategy that could be used to assess the utility of narcotic antagonists in the treatment of opiate addiction. The studies involved heroin self-administration in the research ward setting under blocked (with naltrexone) and unblocked conditions. The designs were also intended to facilitate the correlation of behavioral observations with psychological, social, and physiological data obtained on the research ward and interpreted within a multidisciplinary framework.


Opiate Addiction Opiate User Narcotic Antagonist Heroin Injection Prospective Subject 
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  1. 1.
    Biometric Research Institute Inc. Final Report, National Institute on Drug Abuse (NIDA) Studies Evaluating the Safety of the Narcotic Antagonist, Naltrexone. May 1977, pp. 17–36.Google Scholar
  2. 2.
    Kleber, H., Kinsella, J. K., Riordan, C., Greaves, S., and Sweeney, D. The use of tnlcyclazocine in treating narcotic addicts in a low-intervention setting. Arch. Gen. Psychiatry 30:37, 1974.PubMedCrossRefGoogle Scholar
  3. 3.
    Meyer, R. E., Mirin, S. M., and Altman, J. L. The clinical usefulness of narcotic antagonists: Implications of behavioral research. Am. J. Drug and Alcohol Abuse 2 (3):417–423, 1976.CrossRefGoogle Scholar
  4. 4.
    Resnick, R. B., and Resnick, E. S. A point of view concerning treatment approaches with narcotic antagonists. In: Narcotic Antagonists: Naltrexone, National Institute on Drug Abuse. Research Monogragh Series 9, 1976, pp. 84–88.Google Scholar

Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • Steven M. Mirin
  • Roger E. Meyer

There are no affiliations available

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