The Biosynthesis of Prolactin

  • Richard A. Maurer
  • Roger T. Stone
  • Jack Gorski
Part of the Biochemical Endocrinology book series (BIOEND)


Prolactin biosynthesis involves the transcription and translation of the prolactin gene in specialized cells of the anterior pituitary. These cells are highly adapted to synthesize and secrete large amounts of prolactin (PRL) in response to the correct physiological signals. Thus, these cells are specialized to facilitate the production of a single gene product, PRL. Understanding of PRL biosynthesis will require knowledge of the molecular machinery that permits this specialization in the production of a single peptide, as well as understanding the molecular events involved in the regulation of this process.


Partial Amino Acid Sequence Prolactin Synthesis Prolactin mRNA Cell Free Product Disperse Pituitary Cell 


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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Richard A. Maurer
    • 1
  • Roger T. Stone
    • 2
  • Jack Gorski
    • 3
  1. 1.Department of Physiology and BiophysicsUniversity of IowaIowa CityUSA
  2. 2.Department of ReproductionUnited States Meat Animal Research CenterClay CenterUSA
  3. 3.Departments of Biochemistry and Animal ScienceUniversity of WisconsinMadisonUSA

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