Immunocytochemical Demonstration of Endogenous Gonadotropin-Binding Sites in the Fetal Rat Testis

  • Gwen V. Childs
Part of the Biochemical Endocrinology book series (BIOEND)


Gonadotropins, like most polypeptide hormones, are believed to interact with their target tissue at specific bindings sites on the plasma membrane. Catt et al. (1972) and Leidenberger and Reichert (1972) demonstrated such sites in the rat testis. Other workers have observed that in several species, the number of these sites varies with fetal developmental age (Knorr et al., 1970; Frowein and Engel, 1974; Engel and Frowein, 1974; Ahluwalia et al., 1974; Catt et al., 1975; Weniger and Zeis, 1975; Kolena, 1976; Kaplan et al., 1976). In fact, Frowein and Engel (1974) suggested that one of the first steps in the differentiation process may be the synthesis of gonadotropin receptors.


Sertoli Cell Leydig Cell Rough Endoplasmic Reticulum Human Chorionic Gonadotropin Normal Rabbit Serum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations used in this chapter

hCGβ, rLHβ

β chains of, respectively, human chorionic gonadotropin and rat luteinizing hormone




follicle-stimulating hormone




peroxidase-antiperoxidase complex


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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Gwen V. Childs
    • 1
  1. 1.Departments of Anatomy and Biological SciencesNorthwestern University Medical SchoolChicagoUSA

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