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Studies on the Release and Degradation of Hypothalamic Releasing Hormones by the Hypothalamus and Other CNS Areas in Vitro

  • S. L. Jeffcoate
  • N. White
  • G. W. Bennett
  • J. A. Edwardson
  • E. C. Griffiths
  • R. Forbes
  • J. A. Kelly
Part of the Published Nobel Symposia book series (NOFS, volume 42)

Abstract

During the past decade great advances have been made in the study of the hypophysiotrophic functions of the hypothalamus, culminating in the isolation and structural identification of three peptides: TRH, LH-RH and somatostatin (Sandow and König, 1978). Although several other hormonal (e.g. angiotensin) and non-hormonal peptides (e.g. substance P) are also found in the hypothalamus in addition to the remaining hypophysiotrophic hormones as yet un-identified, our studies have been limited to the three ‘hypothalamic releasing hormones’ whose structure is firmly established.

Keywords

Median Eminence Gonadal Steroid Adult Level Peptide Secretion Neuroscience Letter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • S. L. Jeffcoate
    • 1
  • N. White
    • 1
  • G. W. Bennett
    • 2
  • J. A. Edwardson
    • 2
  • E. C. Griffiths
    • 3
  • R. Forbes
    • 3
  • J. A. Kelly
    • 3
  1. 1.Department of EndocrinologyChelsea Hospital for WomenLondonUK
  2. 2.Department of PhysiologySt. George’s Hospital Medical SchoolLondonUK
  3. 3.Department of PhysiologyUniversity of ManchesterManchesterUK

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