Overview of Session IV: Interactions between Hormones and Neurotransmitters in The Control of Peptidergic Neurons

  • Charles H. Sawyer
Part of the Published Nobel Symposia book series (NOFS, volume 42)


Drs. Fuxe and McCann have discussed many aspects of neurotransmitter systems in the control of anterior pituitary function. It is apparent that acetylcholine, catecholamines, serotonin, histamine and GABA and their receptor stimulants or agonists, receptor blockers and synthesis inhibitors can stimulate or inhibit the secretion of many pituitary tropic hormones by influencing, in most cases, the secretion of peptide releasing hormones from hypothalamic neurons. The effects of catecholamines on gonadotropic function have been most thoroughly studied and perhaps for that reason have been the most controversial. Specifically, the most unresolved problem is the influence of dopamine on LHRH; everyone agrees that it inhibits prolactin secretion and many consider it PIF itself.


Median Eminence Peptidergic Neuron Anterior Pituitary Function Ventral Bundle LHRH Neuron 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Charles H. Sawyer
    • 1
  1. 1.Department of Anatomy and Brain Research InstituteUCLA School of MedicineLos AngelesUSA

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