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Neurotransmitters in the Control of Anterior Pituitary Function

  • S. M. Mc Cann
  • L. Krulich
  • S. R. Ojeda
  • A. Negro-Vilar
  • E. Vijayan
Part of the Published Nobel Symposia book series (NOFS, volume 42)

Abstract

Earlier papers in this volume have amply documented the fact that the anterior pituitary is controlled by a family of hypothalamic releasing and inhibiting hormones which are secreted into the hypophyseal portal vessels in the median eminence (ME) to stimulate or inhibit the release of individual pituitary hormones. The distribution of the peptidergic neurons which synthesize and release the various releasing hormones within the hypothalamus brings these neurons in close contact with a variety of putative synaptic transmitters. The purpose of this chapter will be to review the evidence that some of these transmitters may be involved in controlling release of the releasing and inhibiting horaiones. We will stress results from our laboratory but will include crucial experiments from other laboratories so as to present a balanced picture of the present status of knowledge in this field.

Keywords

Vasoactive Intestinal Peptide Intraventricular Injection Gonadotropin Release Anterior Pituitary Function LHRH Release 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • S. M. Mc Cann
    • 1
  • L. Krulich
    • 1
  • S. R. Ojeda
    • 1
  • A. Negro-Vilar
    • 1
  • E. Vijayan
    • 1
  1. 1.Southwestern Med SchUniv Tx Hlth Sci Ctr at DallasDallasUSA

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