Regulation of Neuropeptide Release in Rat Brain

  • Leslie L. Iversen
  • Thomas M. Jessell
Part of the Published Nobel Symposia book series (NOFS, volume 42)


The discovery of the hypophysiotropic peptides marked a large step forward in our understanding of the central regulation of pituitary function. Little is known, however, of the mechanisms which control the release of these substances from peptidergic neurones. The hypothalamic peptidergic neurones receive numerous synaptic inputs, involving various of the conventional amine and amino acid transmitters. In addition it seems likely that local chemical regulatory mechanisms may operate at the level of the presynaptic peptidergic nerve terminals.


Nerve Terminal Opiate Receptor Tissue Store Peptidergic Neurone Amino Acid Transmitter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • Leslie L. Iversen
    • 1
  • Thomas M. Jessell
    • 1
  1. 1.MRC Neurochemical Pharmacology Unit, Department of PharmacologyUniversity of CambridgeEngland

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